Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MMP2 | P08253 | 2/20 | 0.46 |
| ▸ | DPP4 | P27487 | 3/20 | 0.45 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.45 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.45 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | FAP | Q12884 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6131700 | 0.99 | TSHR (0.47) | TSHRLMNAMMP2DPP4DPP7 | |
| SCHEMBL11651148 | 0.85 | MMP2 (0.49) | TSHRLMNAMMP2DPP4DPP7 | |
| SCHEMBL11907450 | 0.85 | MMP2 (0.46) | TSHRMMP2DPP4DPP7DPP8 | |
| SCHEMBL28998132 | 0.85 | ALDH1A1 (0.47) | LMNAMMP2DPP4DPP7DPP8 | |
| SCHEMBL30410300 | 0.85 | ALDH1A1 (0.47) | LMNAMMP2DPP4DPP7DPP8 | |
| SCHEMBL1068871 | 0.84 | MAPT (0.50) | LMNAMMP2DPP4DPP7DPP8 | |
| SCHEMBL1859542 | 0.84 | MAPT (0.50) | LMNAMMP2DPP4DPP7DPP8 | |
| Hydrochloric Acid SCHEMBL17707255 | 0.83 | ALDH1A1 (0.50) | LMNAMMP2DPP4DPP7DPP8 | |
| Hydrochloric Acid SCHEMBL1859934 | 0.83 | ALDH1A1 (0.50) | LMNAMMP2DPP4DPP7DPP8 | |
| Hydrochloric Acid SCHEMBL1859938 | 0.83 | ALDH1A1 (0.50) | LMNAMMP2DPP4DPP7DPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1293040-C | Process for preparing phenylalanine enamide derivatives | CELLTECH R&D LTD (GB) | 2007-01-03 | — | — | CN | disclosed |
| US-6951943-B2 | Process for the preparation of phenylalanine enamide derivatives | CELLTECH R & D LIMITED (GB) | 2005-10-04 | — | — | US | disclosed |
| CN-1668574-A | Process for preparing phenylalanine enamide derivatives | CELLTECH R&D LTD (GB) | 2005-09-14 | — | — | CN | disclosed |
| EP-1525181-A1 | PROCESS FOR THE PREPARATION OF PHENYLALANINE ENAMIDE DERIVATIVES | Celltech R & D Limited (GB) | 2005-04-27 | — | — | EP | disclosed |
| US-20040073033-A1 | Process for the preparation of phenylalanine enamide derivatives | UCB PHARMA S.A. (BE) | 2004-04-15 | — | — | US | disclosed |
| WO-2004007428-A1 | PROCESS FOR THE PREPARATION OF PHENYLALANINE ENAMIDE DERIVATIVES | CELLTECH R & D LIMITED (GB) | 2004-01-22 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040073033-A1 | Process for the preparation of phenylalanine enamide derivatives | NPY2R, NPY1R, NPR1 | TSHR 1683/4885LMNA 1856/4885MMP2 2815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.