Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.54 |
| ▸ | TYR | P14679 | 1/20 | 0.54 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.54 |
| ▸ | ERN1 | O75460 | 2/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16111393 | 0.83 | ALDH1A1 (0.73) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL4802368 | 0.83 | ALDH1A1 (0.63) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL16046208 | 0.82 | ALDH1A1 (0.71) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL9055047 | 0.82 | ALDH1A1 (0.71) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL96291 | 0.79 | ALDH1A1 (1.00) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL31261798 | 0.78 | ALDH1A1 (0.57) | ALDH1A1RAB9AMAPTMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9456784 | 0.78 | ALDH1A1 (0.96) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| SCHEMBL13168673 | 0.78 | ALDH1A1 (0.69) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| Formaldehyde SCHEMBL28854145 | 0.76 | ALDH1A1 (0.92) | ALDH1A1TRIM24TYRTRIM33ERN1 | |
| Ethylene SCHEMBL4914414 | 0.76 | ALDH1A1 (0.92) | ALDH1A1TRIM24TYRTRIM33ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | disclosed |
| US-6479495-B1 | SIMULTANEOUSLY TREATING DEPRESSION AND MEMORY DYSFUNCTION IN MAMMALS SUFFERING FROM MEMORY DYSFUNCTION AND DEPRESSION | AVENTIS PHARMACEUTICALS INC. | 2002-11-12 | — | — | US | disclosed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | disclosed |