Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
| ▸ | DRD3 | P35462 | 1/20 | 0.49 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6131845 | 0.99 | ALDH1A1 (0.60) | ALDH1A1KDM4ETDP1GAASMN1; SMN2 | |
| SCHEMBL6131769 | 0.87 | ALDH1A1 (0.67) | ALDH1A1KDM4ETDP1GAASMN1; SMN2 | |
| SCHEMBL6131795 | 0.83 | ALDH1A1 (0.67) | ALDH1A1KDM4ETDP1GAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6131911 | 0.81 | ALDH1A1 (0.65) | ALDH1A1KDM4ETDP1GAASMN1; SMN2 | |
| SCHEMBL6131806 | 0.80 | ALDH1A1 (0.60) | ALDH1A1KDM4ETDP1GAASMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL6131844 | 0.79 | ALDH1A1 (0.59) | ALDH1A1KDM4ETDP1GAASMN1; SMN2 | |
| SCHEMBL6131832 | 0.78 | KDM4E (0.63) | ALDH1A1KDM4EPOLBMAPK1KMT2A | |
| Hydrochloric Acid SCHEMBL6131893 | 0.77 | KDM4E (0.62) | ALDH1A1KDM4ESMN1; SMN2POLBMAPK1 | |
| Hydrochloric Acid SCHEMBL6131948 | 0.76 | ADRA1D (0.54) | ALDH1A1KDM4ETDP1GAASMN1; SMN2 | |
| SCHEMBL6131962 | 0.76 | KDM4E (0.62) | ALDH1A1KDM4EGAAALOX15KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | claimed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | claimed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | claimed |