Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTNNB1 | P35222 | 4/20 | 0.54 |
| ▸ | PKM | P14618 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 6/20 | 0.52 |
| ▸ | RAB9A | P51151 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | WNT3A | P56704 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.50 |
| ▸ | RELA | Q04206 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6131977 | 1.00 | CTNNB1 (0.54) | CTNNB1PKMTSHRNPC1RAB9A | |
| SCHEMBL1010516 | 0.82 | TSHR (0.48) | TSHRNPC1RAB9AMAPTMEN1 | |
| SCHEMBL7397215 | 0.79 | ALDH1A1 (0.52) | NPC1RAB9AMEN1KMT2AKDM4E | |
| SCHEMBL9899631 | 0.78 | SMN1; SMN2 (0.47) | NPC1RAB9AMAPTSMN1; SMN2HPGD | |
| SCHEMBL9899633 | 0.78 | SMN1; SMN2 (0.47) | NPC1RAB9AMAPTSMN1; SMN2HPGD | |
| SCHEMBL3267871 | 0.77 | NPC1 (0.44) | TSHRNPC1RAB9AMAPTNPSR1 | |
| SCHEMBL6555910 | 0.77 | CES2 (0.56) | NPC1RAB9AKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL3267872 | 0.77 | NPC1 (0.44) | TSHRNPC1RAB9AMAPTNPSR1 | |
| SCHEMBL6555908 | 0.77 | CES2 (0.56) | NPC1RAB9AKMT2AKDM4ESMN1; SMN2 | |
| SCHEMBL1331949 | 0.76 | CA12 (0.51) | CTNNB1TSHRNPC1RAB9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1214310-B1 | NOVEL PHOTOCHROMIC NAPHTHOPYRANS | TRANSITIONS OPTICAL INC (US) | 2005-04-27 | — | — | EP | disclosed |
| US-6348604-B1 | COMPOUNDS IN WHICH SELECTION AND PLACEMENT OF SUBSTITUENTS CONTROL WAVELENGTH AND/OR INTENSITY OF VISIBLE ABSORBANCE BANDS | PPG INDUSTRIES OHIO, INC. | 2002-02-19 | — | — | US | disclosed |