Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 9/20 | 0.59 |
| ▸ | DRD2 | P14416 | 8/20 | 0.59 |
| ▸ | DRD3 | P35462 | 8/20 | 0.59 |
| ▸ | HTR2A | P28223 | 6/20 | 0.59 |
| ▸ | HTR7 | P34969 | 6/20 | 0.59 |
| ▸ | DRD4 | P21917 | 5/20 | 0.59 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.59 |
| ▸ | DRD1 | P21728 | 2/20 | 0.59 |
| ▸ | DRD5 | P21918 | 2/20 | 0.59 |
| ▸ | HRH1 | P35367 | 2/20 | 0.59 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.50 |
| ▸ | HTR2C | P28335 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6131783 | 0.98 | HTR1A (0.57) | HTR1ADRD2DRD3HTR2AHTR7 | |
| SCHEMBL6131881 | 0.83 | HTR1A (0.58) | HTR1ADRD2DRD3HTR2AHTR7 | |
| SCHEMBL6131854 | 0.83 | HTR1A (0.58) | HTR1ADRD2DRD3HTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL6131899 | 0.82 | HTR1A (0.57) | HTR1ADRD2DRD3HTR2AHTR7 | |
| SCHEMBL6131831 | 0.78 | HTR1A (0.50) | HTR1ADRD2DRD3HTR2AHTR7 | |
| SCHEMBL1509630 | 0.77 | HTR1A (0.83) | HTR1ADRD2DRD3HTR2AHTR7 | |
| SCHEMBL13711971 | 0.76 | KCNH2 (0.71) | HTR1ADRD2DRD3HTR2AHTR7 | |
| SCHEMBL10863750 | 0.75 | HTR1A (0.61) | HTR1ADRD2DRD3HTR2AHTR7 | |
| SCHEMBL4700352 | 0.75 | ADRA1D (0.63) | HTR1ADRD2DRD3HTR2AHTR7 | |
| SCHEMBL27236997 | 0.74 | DRD3 (1.00) | HTR1ADRD2DRD3HTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | disclosed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | disclosed |