Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 2/20 | 0.56 |
| ▸ | DRD4 | P21917 | 2/20 | 0.56 |
| ▸ | HTR2A | P28223 | 2/20 | 0.56 |
| ▸ | HTR7 | P34969 | 2/20 | 0.56 |
| ▸ | DRD3 | P35462 | 2/20 | 0.56 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.56 |
| ▸ | DRD1 | P21728 | 1/20 | 0.56 |
| ▸ | DRD5 | P21918 | 1/20 | 0.56 |
| ▸ | HRH1 | P35367 | 1/20 | 0.56 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.54 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.54 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6131899 | 0.99 | HTR1A (0.57) | HTR1AALDH1A1KDM4ELMNATSHR | |
| SCHEMBL6131854 | 0.84 | HTR1A (0.58) | HTR1AALDH1A1KDM4ELMNATSHR | |
| SCHEMBL6131831 | 0.84 | HTR1A (0.50) | HTR1AALDH1A1KDM4ELMNADRD2 | |
| SCHEMBL6131982 | 0.83 | HTR1A (0.59) | HTR1ALMNADRD2DRD4HTR2A | |
| Hydrochloric Acid SCHEMBL6131783 | 0.81 | HTR1A (0.57) | HTR1ALMNADRD2DRD4HTR2A | |
| SCHEMBL6131908 | 0.80 | ALDH1A1 (0.58) | HTR1AALDH1A1KDM4ELMNATSHR | |
| Hydrochloric Acid SCHEMBL6132036 | 0.79 | ALDH1A1 (0.57) | HTR1AALDH1A1KDM4ELMNATSHR | |
| Oxalic Acid SCHEMBL9077864 | 0.79 | SIGMAR1 (0.74) | ALDH1A1KDM4ELMNATSHRMAPK1 | |
| SCHEMBL6132048 | 0.77 | ALDH1A1 (0.57) | HTR1AALDH1A1KDM4ELMNATSHR | |
| Hydrochloric Acid SCHEMBL6131914 | 0.76 | ALDH1A1 (0.56) | HTR1AALDH1A1KDM4ELMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | claimed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | claimed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | claimed |