Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7688848 | 0.92 | UTS2R (0.50) | UTS2RACHE | |
| Hydrochloric Acid SCHEMBL7680845 | 0.89 | UTS2R (0.48) | UTS2RACHEALDH1A1LMNA | |
| SCHEMBL6131793 | 0.88 | GAA (0.59) | UTS2RPOLBALDH1A1LMNAGAA | |
| Hydrochloric Acid SCHEMBL7684865 | 0.88 | RBP4 (0.48) | UTS2RACHE | |
| Hydrochloric Acid SCHEMBL7688425 | 0.83 | OGA (0.51) | ALDH1A1 | |
| SCHEMBL6131801 | 0.81 | KMT2A (0.52) | UTS2RPOLBADRA1DADRA1AADRA1B | |
| SCHEMBL6131997 | 0.81 | KMT2A (0.50) | UTS2RPOLBADRA1DADRA1AADRA1B | |
| SCHEMBL6131867 | 0.80 | UTS2R (0.52) | UTS2RGAA | |
| SCHEMBL6131934 | 0.80 | UTS2R (0.52) | UTS2RGAA | |
| SCHEMBL6131939 | 0.80 | GAA (0.55) | UTS2RPOLBADRB2ADRB1ADRB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | claimed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | claimed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | claimed |