Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UTS2R | Q9UKP6 | 6/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6131793 | 0.91 | GAA (0.59) | UTS2RGAA | |
| SCHEMBL6131867 | 0.89 | UTS2R (0.52) | UTS2RGAAHTR1AHTR1DHTR1B | |
| SCHEMBL6131776 | 0.88 | UTS2R (0.52) | UTS2RGAAHTR1AHTR1DHTR1B | |
| Hydrochloric Acid SCHEMBL7691264 | 0.87 | UTS2R (0.49) | UTS2RHTR1AHTR1DHTR1B | |
| SCHEMBL6131801 | 0.86 | KMT2A (0.52) | UTS2RGAA | |
| SCHEMBL6131818 | 0.86 | RBP4 (0.51) | UTS2RGAA | |
| SCHEMBL6131984 | 0.83 | UTS2R (0.49) | UTS2RGAA | |
| Hydrochloric Acid SCHEMBL6132096 | 0.81 | UTS2R (0.48) | UTS2RGAA | |
| SCHEMBL6132081 | 0.80 | UTS2R (0.52) | UTS2RGAA | |
| SCHEMBL6131863 | 0.79 | HRH3 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | disclosed |
| US-6479495-B1 | SIMULTANEOUSLY TREATING DEPRESSION AND MEMORY DYSFUNCTION IN MAMMALS SUFFERING FROM MEMORY DYSFUNCTION AND DEPRESSION | AVENTIS PHARMACEUTICALS INC. | 2002-11-12 | — | — | US | disclosed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | disclosed |