Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.59 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6131801 | 0.92 | KMT2A (0.52) | GAAUTS2RPOLBLMNAALDH1A1 | |
| SCHEMBL6131934 | 0.91 | UTS2R (0.52) | GAAUTS2R | |
| SCHEMBL6131867 | 0.91 | UTS2R (0.52) | GAAUTS2RMAPK1 | |
| SCHEMBL6131776 | 0.90 | UTS2R (0.52) | GAAUTS2RLMNAALDH1A1 | |
| SCHEMBL6132081 | 0.88 | UTS2R (0.52) | GAAUTS2RPOLBLMNAALDH1A1 | |
| SCHEMBL6131818 | 0.88 | RBP4 (0.51) | GAAUTS2R | |
| SCHEMBL6131939 | 0.82 | GAA (0.55) | GAAUTS2RPOLBLMNAALDH1A1 | |
| Water SCHEMBL7688250 | 0.81 | GAA (0.54) | GAAUTS2RPOLBLMNAALDH1A1 | |
| Water SCHEMBL7688253 | 0.81 | GAA (0.54) | GAAUTS2RPOLBLMNAALDH1A1 | |
| SCHEMBL6131997 | 0.81 | KMT2A (0.50) | UTS2RPOLBLMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | disclosed |
| US-6479495-B1 | SIMULTANEOUSLY TREATING DEPRESSION AND MEMORY DYSFUNCTION IN MAMMALS SUFFERING FROM MEMORY DYSFUNCTION AND DEPRESSION | AVENTIS PHARMACEUTICALS INC. | 2002-11-12 | — | — | US | disclosed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | disclosed |