Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | UTS2R | Q9UKP6 | 4/20 | 0.49 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6131793 | 0.92 | GAA (0.59) | ALDH1A1GAAUTS2RPOLBLMNA | |
| SCHEMBL6131997 | 0.90 | KMT2A (0.50) | KMT2AMEN1ALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL6131867 | 0.86 | UTS2R (0.52) | GAAUTS2R | |
| SCHEMBL6131934 | 0.86 | UTS2R (0.52) | GAAUTS2R | |
| SCHEMBL6131776 | 0.85 | UTS2R (0.52) | ALDH1A1GAAUTS2RLMNA | |
| SCHEMBL6131771 | 0.85 | KMT2A (0.52) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| Water SCHEMBL6131862 | 0.84 | KMT2A (0.51) | KMT2AMEN1ALDH1A1KDM4EGAA | |
| SCHEMBL6131818 | 0.82 | RBP4 (0.51) | GAAUTS2R | |
| SCHEMBL6132081 | 0.81 | UTS2R (0.52) | ALDH1A1GAAUTS2RADRA1DADRA1A | |
| SCHEMBL6131802 | 0.78 | ADRA1D (0.81) | KMT2AALDH1A1KDM4EADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1032559-A4 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMA INC (US) | 2005-05-25 | — | — | EP | disclosed |
| US-6479495-B1 | SIMULTANEOUSLY TREATING DEPRESSION AND MEMORY DYSFUNCTION IN MAMMALS SUFFERING FROM MEMORY DYSFUNCTION AND DEPRESSION | AVENTIS PHARMACEUTICALS INC. | 2002-11-12 | — | — | US | disclosed |
| EP-1032559-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 2000-09-06 | — | — | EP | disclosed |
| WO-1999016746-A1 | AMINOALKYLPHENOL DERIVATIVES AND RELATED COMPOUNDS | AVENTIS PHARMACEUTICALS INC. (US) | 1999-04-08 | — | — | WO | disclosed |