Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.43 |
| ▸ | PDE4A | P27815 | 2/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7273992 | 0.82 | HPGD (0.48) | HPGDRECQLEPHX1DPP4USP2 | |
| SCHEMBL21026298 | 0.79 | PDE4D (0.45) | HPGDPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL26352077 | 0.79 | HPGD (0.48) | HPGDPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL25059157 | 0.79 | CHRM1 (0.41) | HPGDPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL5271932 | 0.78 | HPGD (0.53) | HPGDRECQLEPHX1DPP4USP2 | |
| SCHEMBL22907100 | 0.77 | HPGD (0.49) | HPGDRECQLEPHX1DPP4USP2 | |
| SCHEMBL19286080 | 0.77 | GPR119 (0.54) | HPGDPDE4DPDE4APDE4BPDE4C | |
| SCHEMBL9032915 | 0.77 | RECQL (0.52) | HPGDRECQLEPHX1USP2SMN1; SMN2 | |
| SCHEMBL18015125 | 0.77 | HPGD (0.51) | HPGDPDE4DRECQLEPHX1DPP4 | |
| SCHEMBL4102689 | 0.77 | EPHX1 (0.47) | HPGDPDE4DPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |