Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 7/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.42 |
| ▸ | HTR3E | A5X5Y0 | 4/20 | 0.42 |
| ▸ | HTR3B | O95264 | 4/20 | 0.42 |
| ▸ | HTR3A | P46098 | 4/20 | 0.42 |
| ▸ | HTR3D | Q70Z44 | 4/20 | 0.42 |
| ▸ | HTR3C | Q8WXA8 | 4/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | NCF1 | P14598 | 1/20 | 0.39 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 3/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | LTA4H | P09960 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132472 | 0.75 | ADRB1 (0.43) | ADRB1SIGMAR1HTR3EHTR3BHTR3A | |
| SCHEMBL17135722 | 0.73 | OPRM1 (0.44) | SIGMAR1ALDH1A1KDM4ETSHRHSD17B10 | |
| SCHEMBL10161191 | 0.72 | HTR3A (0.56) | ADRB1SIGMAR1HTR3EHTR3BHTR3A | |
| SCHEMBL2303349 | 0.70 | CYP2D6 (0.38) | ADRB2NCF1PLD1CYP2D6ALDH1A1 | |
| SCHEMBL5570604 | 0.70 | ADRB1 (0.77) | ADRB1SIGMAR1HTR3EHTR3BHTR3A | |
| SCHEMBL15568523 | 0.70 | TAAR1 (0.41) | SIGMAR1ALDH1A1KDM4EHSD17B10CYP3A4 | |
| SCHEMBL38661103 | 0.68 | ADRB1 (0.53) | ADRB1SIGMAR1HTR3EHTR3BHTR3A | |
| SCHEMBL17276864 | 0.68 | ADRB1 (0.68) | ADRB1SIGMAR1HTR3EHTR3BHTR3A | |
| SCHEMBL4252026 | 0.68 | ADRB1 (0.57) | ADRB1SIGMAR1HTR3EHTR3BHTR3A | |
| SCHEMBL6618068 | 0.67 | ADRB1 (0.52) | ADRB1SIGMAR1HTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |