Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 7/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.44 |
| ▸ | HRH2 | P25021 | 2/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | DRD1 | P21728 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR2C | P28335 | 1/20 | 0.44 |
| ▸ | HTR1E | P28566 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14922733 | 0.86 | MEN1 (0.52) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL6538566 | 0.83 | DRD2 (0.51) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL14922381 | 0.81 | CHRM4 (0.50) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL6133014 | 0.80 | MAPT (0.48) | ALDH1A1MAPTKDM4ETMEM97SIGMAR1 | |
| SCHEMBL751049 | 0.80 | OPRD1 (0.53) | MEN1KMT2AHRH3NPC1RAB9A | |
| SCHEMBL8315425 | 0.79 | OPRD1 (0.54) | MEN1KMT2ALMNAALDH1A1NPC1 | |
| SCHEMBL5702290 | 0.78 | ALDH1A1 (0.47) | MEN1KMT2ALMNAALDH1A1MAPT | |
| SCHEMBL751730 | 0.76 | OPRD1 (0.47) | MEN1KMT2AMAPTHRH2HRH1 | |
| SCHEMBL7556949 | 0.75 | CHRM4 (0.61) | MEN1KMT2ASIGMAR1NPC1RAB9A | |
| SCHEMBL9727540 | 0.74 | NPSR1 (0.68) | MEN1KMT2ALMNAMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |