Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB1 | P08588 | 6/20 | 0.51 |
| ▸ | HTR1A | P08908 | 4/20 | 0.47 |
| ▸ | HTR6 | P50406 | 3/20 | 0.47 |
| ▸ | HTR7 | P34969 | 3/20 | 0.47 |
| ▸ | HTR3A | P46098 | 3/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HTR5A | P47898 | 2/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.47 |
| ▸ | HTR3B | O95264 | 2/20 | 0.47 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.47 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | NCF1 | P14598 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | HTR1D | P28221 | 1/20 | 0.47 |
| ▸ | HTR1B | P28222 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132758 | 0.83 | LGMN (0.52) | ADRB1HTR6HTR3AHTR5AHTR3E | |
| SCHEMBL15834279 | 0.80 | ADRB1 (0.75) | ADRB1HTR1AHTR6HTR7HTR3A | |
| SCHEMBL14804198 | 0.79 | ADRB1 (0.50) | ADRB1HTR1ACYP1A2HSD17B10LMNA | |
| SCHEMBL14117670 | 0.78 | ADRB1 (0.51) | ADRB1LMNAKDM4EALDH1A1HPGD | |
| SCHEMBL22053011 | 0.78 | LGMN (0.44) | HTR1ATSHRHSD17B10LMNAKDM4E | |
| SCHEMBL23536222 | 0.78 | LGMN (0.58) | TSHRHSD17B10LMNAKDM4EALDH1A1 | |
| SCHEMBL14336963 | 0.78 | ALDH1A1 (0.45) | CYP1A2TSHRHSD17B10LMNADRD3 | |
| SCHEMBL16149623 | 0.77 | ADRB1 (0.60) | ADRB1HTR1AHTR6HTR7HTR3A | |
| SCHEMBL31399311 | 0.77 | ADRB1 (0.60) | ADRB1HTR1AHTR6HTR7HTR3A | |
| Hydrochloric Acid SCHEMBL6074396 | 0.77 | LGMN (0.57) | TSHRHSD17B10LMNAKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |