Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | METAP1 | P53582 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.45 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.45 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6133136 | 0.89 | ALDH1A1 (0.52) | ALDH1A1TSHRNPSR1SMN1; SMN2MEN1 | |
| Hydrochloric Acid SCHEMBL6132329 | 0.84 | OPRM1 (0.47) | ALDH1A1TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL22015905 | 0.81 | HPGD (0.65) | ALDH1A1TSHRMETAP1NPSR1SMN1; SMN2 | |
| SCHEMBL20188098 | 0.81 | HPGD (0.65) | ALDH1A1TSHRMETAP1NPSR1SMN1; SMN2 | |
| SCHEMBL6132476 | 0.79 | USP2 (0.58) | ALDH1A1TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL2951762 | 0.79 | HPGD (0.55) | ALDH1A1TSHRNPSR1SMN1; SMN2MEN1 | |
| SCHEMBL2941901 | 0.79 | HTT (0.55) | ALDH1A1TSHRNPSR1SMN1; SMN2MEN1 | |
| SCHEMBL3067260 | 0.78 | ALDH1A1 (0.58) | ALDH1A1TSHRMETAP1NPSR1SMN1; SMN2 | |
| SCHEMBL13328300 | 0.78 | ALDH1A1 (0.59) | ALDH1A1TSHRMETAP1SMN1; SMN2KMT2A | |
| SCHEMBL6132930 | 0.78 | HPGD (0.51) | ALDH1A1TSHRMETAP1NPSR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |