Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.56 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | GFER | P55789 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18711613 | 0.87 | SCD5 (0.56) | USP2MAPK1CYP2C19ALOX12ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6132329 | 0.84 | OPRM1 (0.47) | USP2MAPK1CYP2C19ALOX12ALDH1A1 | |
| SCHEMBL6132853 | 0.79 | ALDH1A1 (0.53) | MAPK1CYP2C19ALDH1A1CYP1A2CYP2C9 | |
| SCHEMBL6132334 | 0.78 | ADRB1 (0.54) | USP2CYP2C19ALDH1A1HSD17B10MAPT | |
| SCHEMBL4670098 | 0.78 | USP2 (0.72) | USP2MAPK1CYP2C19ALOX12ALDH1A1 | |
| SCHEMBL17220377 | 0.77 | SCD5 (0.57) | USP2MAPK1CYP2C19ALDH1A1CYP1A2 | |
| SCHEMBL2881063 | 0.75 | SMN1; SMN2 (0.65) | USP2MAPK1CYP2C19ALOX12ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6132929 | 0.73 | ENPP2 (0.50) | USP2ALDH1A1HPGDMAPTLMNA | |
| SCHEMBL6132956 | 0.73 | USP2 (0.69) | USP2MAPK1CYP2C19ALOX12ALDH1A1 | |
| SCHEMBL6132250 | 0.72 | SMN1; SMN2 (0.59) | MAPK1CYP2C19ALDH1A1MAPTALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |