Hydrochloric Acid

Hydrochloric Acid

SCHEMBL452866

C=C(C)C(=O)NCCN.Cl

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABL1ACEACHEACVR1ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALKAVPR1AAVPR2BCHEBCRCA2CACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCASRCCR5CDK4CDK6CFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNA3CHRNA7CHRNB1CHRNB4CHRNDCHRNECHRNGCOXFA4COXFA4L2CRBNCSF1RCUL4ACYP19A1DDB1DPP4DRD1DRD2DRD3DRD4EDNRAEGFREML4ERBB2ERBB4ESR1ESR2FGFR1FGFR3FLT1FLT3FLT4GAAGABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGHSRGLAGNRHRGPD2GRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BGSTP1HCN4HCRTR1HCRTR2HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HRH2HRH3HSD11B1HSP90AA1HSP90AB1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IMPDH1IMPDH2ITGA2BITGB3ITKJAK1JAK2KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNJ2KCNJ3KCNJ5KCNK3KCNK9KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2KDRKITKLKB1LCKMMAOAMAOBMAPK14METMMP1MMP13MMP7MMP8MT-ND1MT-ND2MT-ND3MT-ND4MT-ND4LMT-ND5MT-ND6NDUFA1NDUFA10NDUFA11NDUFA12NDUFA13NDUFA2NDUFA3NDUFA5NDUFA6NDUFA7NDUFA8NDUFA9NDUFAB1NDUFAF1NDUFAF2NDUFAF3NDUFAF4NDUFB1NDUFB10NDUFB11NDUFB2NDUFB3NDUFB4NDUFB5NDUFB6NDUFB7NDUFB8NDUFB9NDUFC1NDUFC2NDUFS1NDUFS2NDUFS3NDUFS4NDUFS5NDUFS6NDUFS7NDUFS8NDUFV1NDUFV2NDUFV3NR3C1NS5ANTRK1NTRK2NTRK3ODC1OPRD1OPRK1OPRM1P2RY12PAHPARP1PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDE5APDE7APDE7BPDE8APDE8BPDGFRAPDGFRBPIK3CAPIK3CDPNPPOLA1POLA2POLD1POLD2POLD3POLD4POLEPOLE2POLE3PPARGPRIM1PRIM2PRKCAPRKCBPRKCDPRKCEPRKCGPRKCHPRKCIPRKCQPRKCZPRKD1PRKD3PTGS1PTGS2RBX1RENRETROCK1ROCK2RPE65RRM1RRM2RRM2BS1PR1S1PR2S1PR3S1PR4S1PR5SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC18A2SLC6A1SLC6A2SLC6A3SLC6A4SLC9A3SRCTACR1TOP1TOP2ATOP2BTTRTYMPdacAdacBdacCembAfolAftsIgyrAgyrBmrcAmrcBmrdAparCparEpolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB known ✓ P27338 2/20 0.33
PAOX Q6QHF9 3/20 0.39
MEN1 O00255 1/20 0.36
BLM P54132 1/20 0.36
PMP22 Q01453 1/20 0.36
KMT2A Q03164 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
TGFBR1 P36897 1/20 0.35
ALDH1A1 P00352 3/20 0.34
CYP2C9 P11712 1/20 0.34
HPGD P15428 1/20 0.34
ALOX15 P16050 1/20 0.34
CYP2C19 P33261 1/20 0.34
HSD17B10 Q99714 1/20 0.34
CYP1A2 P05177 1/20 0.33
TSHR P16473 1/20 0.33
NFKB1 P19838 1/20 0.33
KDM4E B2RXH2 3/20 0.31
MAPK1 P28482 1/20 0.31
HIF1A Q16665 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL7770837 0.98 PAOX (0.38) PAOXMEN1BLMPMP22KMT2A
SCHEMBL50166 0.98
Ammonia Solution, Strong SCHEMBL27914279 0.95 PAOX (0.39) PAOXMEN1BLMPMP22KMT2A
Trimethylammonium SCHEMBL27672173 0.94 PAOX (0.35) PAOXMEN1BLMPMP22KMT2A
Chloromethane SCHEMBL1803774 0.93 PAOX (0.38) PAOXMEN1BLMPMP22KMT2A
Trimethylammonium SCHEMBL27741449 0.91 PAOX (0.36) PAOXMEN1BLMPMP22KMT2A
Acetic Acid SCHEMBL7770839 0.91 TGFBR1 (0.37) PAOXMEN1BLMPMP22KMT2A
Phosphoric Acid SCHEMBL9950456 0.90 PAOX (0.35) PAOXMEN1BLMPMP22KMT2A
Hydrochloric Acid SCHEMBL82715 0.87 PAOX (0.50) PAOXPMP22TGFBR1KDM4EMAPK1
Hydrochloric Acid SCHEMBL28412040 0.87 PAOX (0.50) PAOXPMP22TGFBR1KDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 618 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12595396-B2 Acid resistant filter media ENTEGRIS, INC. (US) 2026-04-07 US claimed
CN-120114407-A Composite magnetic photo-thermal microsphere, preparation method thereof, embolic preparation and application 南方科技大学 2025-06-10 CN claimed
EP-4314154-B1 WATER-SOLUBLE POLYMER TO PREVENT NON-SPECIFIC ADSORPTION N LAB TECH CENTER PTE LTD (SG) 2025-04-23 EP claimed
EP-3463631-B1 COATED POROUS POLYMERIC MEMBRANES ENTEGRIS INC (US) 2024-09-04 EP claimed
US-20240182698-A1 WATER-SOLUBLE POLYMER TO PREVENT NON-SPECIFIC ADSORPTION N-LAB TECHNOLOGY CENTER PTE. LTD. (SG) 2024-06-06 US claimed
CN-118125951-A Sulfonyl zwitterionic polymer with antibacterial function, and preparation method and application thereof 河南科技大学 2024-06-04 CN claimed
CN-117860433-A Intraocular lens conveying device and preparation method thereof 上海新耀湃科医疗科技股份有限公司 2024-04-12 CN claimed
EP-4314154-A1 WATER-SOLUBLE POLYMER TO PREVENT NON-SPECIFIC ADSORPTION N-Lab Technology Center Pte. Ltd. (SG) 2024-02-07 EP claimed
CN-114230678-B Photocrosslinked hydrogel embolism system for intravascular treatment and application method 珠海通桥医疗科技有限公司 2023-09-01 CN claimed
US-11731085-B2 Coated porous polymeric membranes ENTEGRIS, INC. (US) 2023-08-22 US claimed
US-20150206793-A1 POLYMER GRAFTING FOR ENHANCED DIELECTRIC AND INTERCONNECT MATERIAL ADHESION INTEL CORPORATION 2015-07-23 US claimed
CN-102643218-B Fluorescent material and preparation method and application thereof UNIV HUAZHONG SCIENCE TECH 2014-06-18 CN claimed
US-20100051461-A1 Poly and Copolyn(N-Vinylamide)s and their use in Capillary Electrophoresis Life Technologies Corporation (US) 2010-03-04 US claimed
EP-2053067-A1 Poly and copoly (N-vinylamide)s and their use in capillary electrophoresis Applied Biosystems Inc. (US) 2009-04-29 EP claimed
EP-1636279-B1 POLY AND COPOLY (N -VINYLAMIDE)S AND THEIR USE IN CAPILLARY ELECTROPHORESIS APPLIED BIOSYSTEMS (US) 2009-02-18 EP claimed
US-20060181587-A1 Ink set and media for ink-jet printing HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. 2006-08-17 US claimed
EP-1636279-A1 POLY AND COPOLY (N -VINYLAMIDE)S AND THEIR USE IN CAPILLARY ELECTROPHORESIS Applera Corporation (US) 2006-03-22 EP claimed
US-20050025741-A1 Copolymers with (meth)acrylamides; improved separation of polynucleotides APPLIED BIOSYSTEMS, LLC 2005-02-03 US claimed
WO-2004104054-A1 POLY AND COPOLY (N-VINYLAMIDE)S AND THEIR USE IN CAPILLARY ELECTROPHORESIS APPLERA CORPORATION (US) 2004-12-02 WO claimed
US-20030152961-A1 Polyfunctional support material for complex nucleic acid analysis BENDZKO PETER (DE) 2003-08-14 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12595396-B2 Acid resistant filter media SDC2, F7, SDC1 MAOB 3116/4885PAOX 1761/4885MEN1 1995/4885
US-20050025741-A1 Copolymers with (meth)acrylamides; improved separation of polynucleotides POLI, PCNA, POLL MAOB 3227/4885PAOX 1846/4885MEN1 2730/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.