Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | CCR1 | P32246 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.50 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3320633 | 0.89 | CCR1 (0.55) | CCR1 | |
| SCHEMBL6135862 | 0.85 | MEN1 (0.47) | MEN1KMT2ACCR1POLB | |
| SCHEMBL13798752 | 0.84 | MEN1 (0.55) | MEN1KMT2ACCR1 | |
| SCHEMBL3321981 | 0.84 | CCR1 (0.48) | CCR1 | |
| SCHEMBL2226429 | 0.82 | CTSK (0.50) | MEN1KMT2ACCR1 | |
| SCHEMBL2226432 | 0.82 | CTSK (0.50) | MEN1KMT2ACCR1 | |
| SCHEMBL3318502 | 0.81 | SRD5A1 (0.55) | KMT2ACCR1L3MBTL1 | |
| SCHEMBL3320205 | 0.81 | CCR1 (0.48) | CCR1 | |
| SCHEMBL3322049 | 0.80 | CYP3A4 (0.49) | KMT2ACCR1 | |
| SCHEMBL7370466 | 0.80 | ALDH1A1 (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6908911-B1 | Antibacterial agents | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2005-06-21 | — | — | US | disclosed |
| EP-1210330-B1 | ANTIBACTERIAL AGENTS | VERNALIS OXFORD LTD (GB) | 2005-04-20 | — | — | EP | disclosed |
| EP-1210330-A1 | ANTIBACTERIAL AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001010835-A1 | ANTIBACTERIAL AGENTS | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2001-02-15 | — | — | WO | disclosed |