Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 6/20 | 0.46 |
| ▸ | MMP13 | P45452 | 3/20 | 0.46 |
| ▸ | CCR1 | P32246 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 2/20 | 0.42 |
| ▸ | CTSS | P25774 | 2/20 | 0.42 |
| ▸ | CTSK | P43235 | 2/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | CASP2 | P42575 | 1/20 | 0.42 |
| ▸ | CASP4 | P49662 | 1/20 | 0.42 |
| ▸ | CASP5 | P51878 | 1/20 | 0.42 |
| ▸ | CASP7 | P55210 | 1/20 | 0.42 |
| ▸ | CASP9 | P55211 | 1/20 | 0.42 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.42 |
| ▸ | CASP10 | Q92851 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3318363 | 0.87 | SRD5A1 (0.46) | MMP1MMP13CCR1CTSBCTSS | |
| SCHEMBL3319639 | 0.87 | CTSL (0.43) | MMP1MMP13CCR1CTSSCTSK | |
| SCHEMBL3323193 | 0.87 | CTSS (0.43) | MMP1MMP13CCR1CTSBCTSS | |
| SCHEMBL3317918 | 0.86 | MMP1 (0.45) | MMP1MMP13CTSSCTSKCTSL | |
| SCHEMBL6135874 | 0.85 | MEN1 (0.55) | MEN1KMT2ACCR1POLB | |
| SCHEMBL2794578 | 0.85 | MMP1 (0.41) | MMP1MMP13CCR1CTSBCTSS | |
| SCHEMBL3320473 | 0.85 | CTSL (0.41) | MEN1KMT2AMMP1MMP13CCR1 | |
| SCHEMBL2797087 | 0.83 | THRB (0.39) | MMP1MMP13CCR1CTSBCTSS | |
| SCHEMBL2791631 | 0.81 | MMP1 (0.37) | MMP1MMP13CCR1CTSBCTSS | |
| SCHEMBL5914490 | 0.81 | JAK2 (0.43) | MMP1MMP13CTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6908911-B1 | Antibacterial agents | BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) | 2005-06-21 | — | — | US | disclosed |
| EP-1210330-B1 | ANTIBACTERIAL AGENTS | VERNALIS OXFORD LTD (GB) | 2005-04-20 | — | — | EP | disclosed |