Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24241764 | 0.91 | MAPT (0.44) | ALDH1A1HPGDMAPTMEN1MAPK1 | |
| SCHEMBL2317085 | 0.91 | ALDH1A1 (0.36) | ALDH1A1HPGDMAPTMEN1KMT2A | |
| SCHEMBL24241601 | 0.91 | ALDH1A1 (0.36) | ALDH1A1HPGDMAPTMEN1MAPK1 | |
| Hydrochloric Acid SCHEMBL11729437 | 0.88 | ALDH1A1 (0.45) | ALDH1A1HPGDMAPTMEN1MAPK1 | |
| SCHEMBL22505234 | 0.88 | KDM4E (0.44) | ALDH1A1MAPTNPC1RAB9AKDM4E | |
| SCHEMBL6468303 | 0.86 | ALDH1A1 (0.35) | ALDH1A1HPGDMAPTMEN1MAPK1 | |
| SCHEMBL9360908 | 0.85 | CLK1 (0.31) | ALDH1A1HPGDMAPTKDM4E | |
| SCHEMBL6698057 | 0.84 | ALDH1A1 (0.36) | ALDH1A1HPGDMAPTMEN1MAPK1 | |
| SCHEMBL24534547 | 0.81 | ALDH1A1 (0.47) | ALDH1A1HPGDMAPTMEN1MAPK1 | |
| SCHEMBL10583841 | 0.79 | ALOX15 (0.39) | ALDH1A1HPGDMAPTMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4785070-A | THERMAL CYCLODEHYDRATION OF AN AZLACTONE OR 4,4-DISUBSTITUTED 2-OXAZOLIN-5-ONE AND DIAMINE; WATER SOLUBILITY | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1988-11-15 | — | — | US | claimed |
| EP-0185493-A2 | Imidazolinone-containing polymers and copolymers | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1986-06-25 | — | — | EP | claimed |
| EP-0019061-B1 | PROCESS FOR PRODUCING AROMATIC POLYESTERS HAVING INCREASED DEGREES OF POLYMERIZATION AND MOULDED ARTICLES COMPOSED OF THESE POLYESTERS | TEIJIN LIMITED (JP) | 1984-08-08 | — | — | EP | claimed |
| US-4291152-A | CHAIN EXTENSION WITH BICYCLIC OXAZINONE OR OXAZOLONE | TEIJIN LIMITED (JP) | 1981-09-22 | — | — | US | claimed |
| EP-0019061-A1 | Process for producing aromatic polyesters having increased degrees of polymerization and moulded articles composed of these polyesters | TEIJIN LIMITED (JP) | 1980-11-26 | — | — | EP | claimed |
| EP-0737231-B2 | THERMAL STABILIZED RESIN COMPOSITIONS | KOLON INC (KR) | 2005-11-02 | — | — | EP | disclosed |
| US-20040068059-A1 | Aliphatic polyester copolymer and process for producing the same, biodegradable resin molding based on aliphatic polyester, and lactone-containing resin | DAICEL CHEMICAL INDUSTRIES LTD. (JP) | 2004-04-08 | — | — | US | disclosed |
| EP-1354908-A1 | ALIPHATIC POLYESTER COPOLYMER AND PROCESS FOR PRODUCING THE SAME, BIODEGRADABLE RESIN MOLDING BASED ON ALIPHATIC POLYESTER, AND LACTONE-CONTAINING RESIN | DAICEL CHEMICAL INDUSTRIES, Ltd. (JP) | 2003-10-22 | — | — | EP | disclosed |
| EP-0710684-B1 | Preparation process of polyhydroxycarboxylic acid | MITSUI CHEMICALS INC (JP) | 2001-01-31 | — | — | EP | disclosed |
| EP-0737231-B1 | THERMAL STABILIZED RESIN COMPOSITIONS | KOLON INC (KR) | 2000-03-08 | — | — | EP | disclosed |
| US-5849820-A | Thermal stabilized resin compositions | KOLON INDUSTRIES, INC. (KR) | 1998-12-15 | — | — | US | disclosed |
| EP-0737231-A1 | THERMAL STABILIZED RESIN COMPOSITIONS | KOLON INDUSTRIES, INC. (KR) | 1996-10-16 | — | — | EP | disclosed |
| US-4705824-A | Poly(5-imidazolone) and process therefor | W. R. GRACE & CO. (US) | 1987-11-10 | — | — | US | disclosed |
| EP-0185493-A2 | Imidazolinone-containing polymers and copolymers | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1986-06-25 | — | — | EP | disclosed |
| EP-0019061-B1 | PROCESS FOR PRODUCING AROMATIC POLYESTERS HAVING INCREASED DEGREES OF POLYMERIZATION AND MOULDED ARTICLES COMPOSED OF THESE POLYESTERS | TEIJIN LIMITED (JP) | 1984-08-08 | — | — | EP | disclosed |
| EP-0020944-B1 | PROCESS FOR PRODUCING AROMATIC POLYESTERS HAVING AN INCREASED DEGREE OF POLYMERISATION, THESE AROMATIC POLYESTERS, PROCESS FOR PRODUCING MOLDED ARTICLES COMPOSED THEREOF, AND THESE MOLDED ARTICLES | TEIJIN LIMITED (JP) | 1983-07-27 | — | — | EP | disclosed |
| US-4331800-A | CHAIN EXTENSION WITH A BIS/CYCLIC IMINOETHER | TEIJIN LIMITED (JP) | 1982-05-25 | — | — | US | disclosed |
| US-4291152-A | CHAIN EXTENSION WITH BICYCLIC OXAZINONE OR OXAZOLONE | TEIJIN LIMITED (JP) | 1981-09-22 | — | — | US | disclosed |
| EP-0020944-A1 | Process for producing aromatic polyesters having an increased degree of polymerisation, these aromatic polyesters, process for producing molded articles composed thereof, and these molded articles | TEIJIN LIMITED (JP) | 1981-01-07 | — | — | EP | disclosed |
| EP-0019061-A1 | Process for producing aromatic polyesters having increased degrees of polymerization and moulded articles composed of these polyesters | TEIJIN LIMITED (JP) | 1980-11-26 | — | — | EP | disclosed |