SCHEMBL6136492

SCHEMBL6136492

[O-][n+]1cc(Br)ccc1S

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6136319 0.74
SCHEMBL6136531 0.70
SCHEMBL1008408 0.70
SCHEMBL304451 0.70
SCHEMBL6136557 0.70
SCHEMBL4992062 0.70
SCHEMBL11730335 0.68 LMNA (0.43)
SCHEMBL10330647 0.65 IDH1 (0.37)
SCHEMBL17648125 0.65 HDAC8 (0.31)
SCHEMBL2160030 0.65 PLCG1 (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1435953-A4 ANTIVESICANT COMPOUNDS AND METHODS OF MAKING AND USING THEREOF US ARMY MED RES MAT COMMAND (US) 2005-05-04 EP claimed
EP-1435953-A1 ANTIVESICANT COMPOUNDS AND METHODS OF MAKING AND USING THEREOF U.S. Army Medical Research and Materiel Command (US) 2004-07-14 EP claimed
US-20030055090-A1 Antivesicant compounds and methods of making and using thereof LG DISPLAY CO., LTD. (KR) 2003-03-20 US claimed
WO-2003011292-A1 ANTIVESICANT COMPOUNDS AND METHODS OF MAKING AND USING THEREOF U.S. ARMY MEDICAL RESEARCH AND MATERIEL COMMAND (US) 2003-02-13 WO claimed
EP-1435953-A4 ANTIVESICANT COMPOUNDS AND METHODS OF MAKING AND USING THEREOF US ARMY MED RES MAT COMMAND (US) 2005-05-04 EP disclosed
EP-1435953-A1 ANTIVESICANT COMPOUNDS AND METHODS OF MAKING AND USING THEREOF U.S. Army Medical Research and Materiel Command (US) 2004-07-14 EP disclosed
US-6664280-B2 For decontaminating an area exposed to a vesicant agent; for therapy of prophylaxis or inhibiting injuries induced by a vesicant agent, such as bis-2-chloroethylsulfide (HD) THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY 2003-12-16 US disclosed
US-20030055090-A1 Antivesicant compounds and methods of making and using thereof LG DISPLAY CO., LTD. (KR) 2003-03-20 US disclosed
WO-2003011292-A1 ANTIVESICANT COMPOUNDS AND METHODS OF MAKING AND USING THEREOF U.S. ARMY MEDICAL RESEARCH AND MATERIEL COMMAND (US) 2003-02-13 WO disclosed
EP-0128249-B1 ANTIMICROBIAL DISULFIDE PRODRUGS SMITHKLINE BECKMAN CORPORATION (US) 1988-08-03 EP disclosed
EP-0128249-A2 Antimicrobial disulfide prodrugs SMITHKLINE BECKMAN CORPORATION (US) 1984-12-19 EP disclosed
US-4427582-A Antimicrobial disulfide prodrugs SMITHKLINE BECKMAN CORPORATION (US) 1984-01-24 US disclosed