Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | CASP1 | P29466 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | CASP7 | P55210 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5705033 | 0.89 | CA2 (0.45) | CA2PDE10AKDM4CHSD17B1HSD17B2 | |
| SCHEMBL7807362 | 0.86 | CA2 (0.41) | CA2HSD17B1HSD17B2KDM4EALDH1A1 | |
| SCHEMBL6136783 | 0.78 | PDE10A (0.50) | CA2PDE10AKDM4CHSD17B1HSD17B2 | |
| SCHEMBL6136947 | 0.74 | CA1 (0.46) | CA2PDE10AKDM4CKDM4EALDH1A1 | |
| SCHEMBL6136958 | 0.74 | LCK (0.38) | CA2PDE10AKDM4CKDM4EALDH1A1 | |
| SCHEMBL6136853 | 0.74 | KDM4E (0.44) | PDE10AKDM4CHSD17B1HSD17B2KDM4E | |
| SCHEMBL1381310 | 0.73 | PDE10A (0.41) | CA2PDE10AKDM4CKDM4EALDH1A1 | |
| SCHEMBL1380335 | 0.72 | KDM4E (0.43) | CA2PDE10AKDM4CKDM4EALDH1A1 | |
| SCHEMBL5712475 | 0.72 | CA2 (0.43) | CA2HSD17B1HSD17B2KDM4EALDH1A1 | |
| SCHEMBL6136824 | 0.72 | ALOX15 (0.49) | PDE10AKDM4CKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1153917-B1 | p-Aminophenol derivatives and colorants containing them | WELLA AG (DE) | 2005-04-13 | — | — | EP | claimed |
| US-6592631-B2 | Useful as developer compounds in oxidation dye compositions for keratin fibers. | WELLA AG (DE) | 2003-07-15 | — | — | US | claimed |
| US-20010054207-A1 | p-aminophenol derivative compounds and dye compositions containing same | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2001-12-27 | — | — | US | claimed |
| EP-1153917-A1 | p-Aminophenol derivatives and colorants containing them | Wella Aktiengesellschaft (DE) | 2001-11-14 | — | — | EP | claimed |
| EP-1153917-B1 | p-Aminophenol derivatives and colorants containing them | WELLA AG (DE) | 2005-04-13 | — | — | EP | disclosed |
| US-6592631-B2 | Useful as developer compounds in oxidation dye compositions for keratin fibers. | WELLA AG (DE) | 2003-07-15 | — | — | US | disclosed |
| US-20010054207-A1 | p-aminophenol derivative compounds and dye compositions containing same | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2001-12-27 | — | — | US | disclosed |
| EP-1153917-A1 | p-Aminophenol derivatives and colorants containing them | Wella Aktiengesellschaft (DE) | 2001-11-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010054207-A1 | p-aminophenol derivative compounds and dye compositions containing same | KRT18, AASDHPPT, S100P | CA2 3119/4885PDE10A 3344/4885KDM4C 125/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.