Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.38 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 5/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 2/20 | 0.37 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 3/20 | 0.33 |
| ▸ | PRKCI | P41743 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | TTR | P02766 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5712444 | 0.78 | TSHR (0.37) | HSD17B1HSD17B2MAPTLMNAKDM4E | |
| SCHEMBL5712543 | 0.78 | ALOX15 (0.39) | CA2STAT3HSD17B1HSD17B2MAPT | |
| SCHEMBL5712512 | 0.75 | TSHR (0.36) | HSD17B1HSD17B2MAPTLMNAKDM4E | |
| SCHEMBL5712518 | 0.75 | ALOX15 (0.33) | MAPTLMNAKDM4ETHRBPOLB | |
| SCHEMBL5712440 | 0.73 | MAPT (0.39) | STAT3HSD17B1HSD17B2MAPTLMNA | |
| SCHEMBL2936107 | 0.73 | HSD17B1 (0.48) | HSD17B1MAPTLMNATHRBPRKCI | |
| SCHEMBL5712435 | 0.73 | LMNA (0.47) | HSD17B1HSD17B2MAPTLMNAKDM4E | |
| SCHEMBL5705033 | 0.73 | CA2 (0.45) | CA2HSD17B1HSD17B2MAPTKDM4E | |
| SCHEMBL10367391 | 0.73 | MAPT (0.52) | CA2HSD17B1HSD17B2MAPTLMNA | |
| SCHEMBL5712467 | 0.72 | GAA (0.44) | CA2LMNATHRBALDH1A1ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7132001-B2 | 3-aminophenol derivatives and dyes that contain these compounds while serving to dye keratin fibers | WELLA AG (DE) | 2006-11-07 | — | — | US | claimed |
| EP-1495015-B1 | 3-AMINOPHENOL DERIVATIVES AND DYES THAT CONTAIN THESE COMPOUNDS WHILE SERVING TO DYE KERATIN FIBERS | WELLA AG (DE) | 2006-04-12 | — | — | EP | claimed |
| CN-1646518-A | 3-aminophenol derivatives and keratin fibre colorants comprising these compounds | P & G CLAIROL INC (US) | 2005-07-27 | — | — | CN | claimed |
| EP-1495015-A1 | 3-AMINOPHENOL DERIVATIVES AND DYES THAT CONTAIN THESE COMPOUNDS WHILE SERVING TO DYE KERATIN FIBERS | Wella Aktiengesellschaft (DE) | 2005-01-12 | — | — | EP | claimed |
| US-20040231064-A1 | 3-Aminophenol derivatives and dyes that contain these compounds while serving to dye keratin fibers | WELLA AKTIENGESELLSCHAFT (DE) | 2004-11-25 | — | — | US | claimed |
| WO-2003087084-A1 | 3-AMINOPHENOL DERIVATIVES AND DYES THAT CONTAIN THESE COMPOUNDS WHILE SERVING TO DYE KERATIN FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 2003-10-23 | — | — | WO | claimed |
| CN-100549003-C | 3-aminophenol derivatives and keratin fibre colorants comprising these compounds | P & G CLAIROL INC (US) | 2009-10-14 | — | — | CN | disclosed |
| US-7132001-B2 | 3-aminophenol derivatives and dyes that contain these compounds while serving to dye keratin fibers | WELLA AG (DE) | 2006-11-07 | — | — | US | disclosed |
| EP-1495015-B1 | 3-AMINOPHENOL DERIVATIVES AND DYES THAT CONTAIN THESE COMPOUNDS WHILE SERVING TO DYE KERATIN FIBERS | WELLA AG (DE) | 2006-04-12 | — | — | EP | disclosed |
| CN-1646518-A | 3-aminophenol derivatives and keratin fibre colorants comprising these compounds | P & G CLAIROL INC (US) | 2005-07-27 | — | — | CN | disclosed |
| EP-1495015-A1 | 3-AMINOPHENOL DERIVATIVES AND DYES THAT CONTAIN THESE COMPOUNDS WHILE SERVING TO DYE KERATIN FIBERS | Wella Aktiengesellschaft (DE) | 2005-01-12 | — | — | EP | disclosed |
| US-20040231064-A1 | 3-Aminophenol derivatives and dyes that contain these compounds while serving to dye keratin fibers | WELLA AKTIENGESELLSCHAFT (DE) | 2004-11-25 | — | — | US | disclosed |
| WO-2003087084-A1 | 3-AMINOPHENOL DERIVATIVES AND DYES THAT CONTAIN THESE COMPOUNDS WHILE SERVING TO DYE KERATIN FIBERS | WELLA AKTIENGESELLSCHAFT (DE) | 2003-10-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040231064-A1 | 3-Aminophenol derivatives and dyes that contain these compounds while serving to dye keratin fibers | KRT18, JUP, IK | CA2 836/4885STAT3 1386/4885HSD17B1 2716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.