SCHEMBL6137447

SCHEMBL6137447

O=C(Cl)c1sc(C(F)(F)F)nc1C(F)(F)F

nearest known ligand 0.37

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.37
ALDH1A1 P00352 1/20 0.37
POLB P06746 1/20 0.36
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
HSD11B1 P28845 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6137459 0.82 MAPT (0.40) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL2310145 0.81 MEN1 (0.49) MAPTALDH1A1POLBMEN1KMT2A
Hydrochloric Acid SCHEMBL6137451 0.81 MAPT (0.39) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL883065 0.81 MAPT (0.37) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL2199155 0.79 MAPT (0.56) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL9644328 0.79 ALDH1A1 (0.39) MAPTALDH1A1POLB
SCHEMBL16346826 0.79 MEN1 (0.31) MEN1KMT2A
SCHEMBL28070522 0.79 ALDH1A1 (0.41) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL27993175 0.79 MAPT (0.37) MAPTALDH1A1POLBMEN1KMT2A
SCHEMBL28363818 0.76 MAPT (0.35) MAPTALDH1A1POLBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1110956-B1 The use of 5-carboxanilido-2,4-bis-trifluoromethylthiazoles to control rice blast DOW AGROSCIENCES LLC (US) 2005-02-23 EP disclosed
EP-1112688-B1 A method to control termites DOW AGROSCIENCES LLC (US) 2004-09-22 EP disclosed
US-6423730-B1 FLUORINATED TRIAZOLE RING CONTAINING COMPOUND DOW AGROSCIENCES LLC 2002-07-23 US disclosed
US-6372769-B1 APPLYING FUNGICIDES TO RICE DOW AGROSCIENCES LLC 2002-04-16 US disclosed
EP-1112688-A1 A method to control termites ROHM AND HAAS COMPANY (US) 2001-07-04 EP disclosed
EP-1110956-A1 5-carboxanilido-2,4-bis-trifluoromethylthiazoles and their use to control rice blast ROHM AND HAAS COMPANY (US) 2001-06-27 EP disclosed
EP-1110454-A2 5-Carboxanilido-haloalkylthiazoles as antimicrobial and marine antifouling agents ROHM AND HAAS COMPANY (US) 2001-06-27 EP disclosed
EP-1108714-A1 Microbicidal salts of 5-carboxanilido-haloalkylthiazoles ROHM AND HAAS COMPANY (US) 2001-06-20 EP disclosed