SCHEMBL6138430

SCHEMBL6138430

O=C(O)c1cccc(C2(c3cccc(C(=O)O)c3C(=O)O)c3ccccc3-c3ccccc32)c1C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.45
ALOX15 P16050 1/20 0.45
HNF4A P41235 1/20 0.44
THRB P10828 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
FOLH1 Q04609 1/20 0.44
MAPT P10636 2/20 0.43
MYC P01106 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
LMNA P02545 1/20 0.43
HSD17B10 Q99714 1/20 0.43
AKR1C3 P42330 1/20 0.41
LIG1 P18858 1/20 0.41
NR4A1 P22736 1/20 0.40
NR4A2 P43354 1/20 0.40
NR4A3 Q92570 1/20 0.40
APEX1 P27695 1/20 0.40
CDC25B P30305 1/20 0.40
KDM4E B2RXH2 1/20 0.39
CA12 O43570 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2709809 0.85 ALDH1A1 (0.52) ALDH1A1ALOX15HNF4ATHRBTDP1
SCHEMBL38651343 0.85 ALDH1A1 (0.52) ALDH1A1ALOX15HNF4ATHRBTDP1
SCHEMBL6869548 0.82 ALDH1A1 (0.51) ALDH1A1ALOX15HNF4ATHRBTDP1
SCHEMBL27869573 0.81 HNF4A (0.45) ALDH1A1ALOX15HNF4ATHRBTDP1
SCHEMBL31613861 0.81 NR4A1 (0.52) ALDH1A1ALOX15HNF4ATHRBTDP1
SCHEMBL23302252 0.80 MCL1 (0.43) ALDH1A1ALOX15HNF4ATHRBTDP1
SCHEMBL5321232 0.78 ALDH1A1 (0.59) ALDH1A1ALOX15HNF4AFOLH1MAPT
SCHEMBL6941870 0.78 ALDH1A1 (0.59) ALDH1A1ALOX15HNF4AFOLH1MAPT
SCHEMBL5321419 0.78 ALDH1A1 (0.59) ALDH1A1ALOX15HNF4AFOLH1MAPT
Bicarbonate SCHEMBL6863236 0.78 THRB (0.60) ALDH1A1THRBTDP1MAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1993009074-A2 CHLORINATION PROCESS, ALKYLATION OF PRODUCTS OF SAID PROCESS AND SOME PRODUCTS THEREOF THE DOW CHEMICAL COMPANY (US) 1993-05-13 WO claimed
WO-2023106056-A1 CROSSLINKED ACRYLIC POLYMER PARTICLE FOR PRODUCING SEPARATORS 三菱鉛筆株式会社 2023-06-15 WO disclosed
EP-1117102-B1 Method of manufacturing material for forming insulating film JSR CORP (JP) 2005-08-10 EP disclosed
US-6642352-B2 Providing a silicon inorganic polymer compound or polyarylenes or polyphenylene ether organic polymer compound, treating the polymeric compound with a zeta-potential producing filter material, and producing curable polymer compound JSR CORPORATION (JP) 2003-11-04 US disclosed
EP-0844283-B1 Curable resin composition and cured products JSR CORP (JP) 2002-10-09 EP disclosed
US-6313233-B1 CAN BE CURED AND FABRICATED WITHOUT PRODUCING NO CRACKS INTO A CURED PRODUCT SUCH AS A SEMICONDUCTOR DEVICE HAVING A LOW DIELECTRIC CONSTANT, HIGH HEAT RESISTANCE AND MOISTURE RESISTANCE, SUPERIOR ADHESION TO VARIOUS SUBSTRATE MATERIALS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 2001-11-06 US disclosed
US-20010009936-A1 Method of manufacturing material for forming insulating film JSR CORPORATION (JP) 2001-07-26 US disclosed
US-6011123-A ORGANOSILANE COMPOUND; POLYAMIC ACIDS HAVING A HYDROLYZABLE SILYL GROUP OR CARBOXYLIC ACID ANHYDRIDE GROUP, OR BOTH, AND POLYIMIDES HAVING A HYDROLYZABLE SILYL GROUP OR CARBOXYLIC ACID ANHYDRIDE GROUP, OR BOTH. JSR CORPORATION (JP) 2000-01-04 US disclosed
EP-0844283-A1 Curable resin composition and cured products JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1998-05-27 EP disclosed
US-5578737-A SUBSTITUTED FLUORENES, MONOMERS FOR HIGH PERFORMANCE POLYMERS THE DOW CHEMICAL COMPANY (US) 1996-11-26 US disclosed
US-5387725-A Chlorinating compounds having acidic protons with a perchloro-alkane and aqueous base in the presence of a tetraalkyl-ammonium hydroxide phase transfer catalyst THE DOW CHEMICAL COMPANY (US) 1995-02-07 US disclosed
EP-0611366-A1 CHLORINATION PROCESS, ALKYLATION OF PRODUCTS OF SAID PROCESS AND SOME PRODUCTS THEREOF THE DOW CHEMICAL COMPANY (US) 1994-08-24 EP disclosed
WO-1993009074-A2 CHLORINATION PROCESS, ALKYLATION OF PRODUCTS OF SAID PROCESS AND SOME PRODUCTS THEREOF THE DOW CHEMICAL COMPANY (US) 1993-05-13 WO disclosed