Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.41 |
| ▸ | EBP | Q15125 | 2/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.41 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.41 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.41 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6049249 | 0.85 | PLAAT3 (0.42) | TRPV1DRD2SIGMAR1EBPTMEM97 | |
| SCHEMBL6049293 | 0.84 | DRD2 (0.43) | DRD2SIGMAR1EBPTMEM97 | |
| SCHEMBL6140314 | 0.82 | DRD2 (0.47) | DRD2SIGMAR1EBPTMEM97PLAAT3 | |
| SCHEMBL6049294 | 0.80 | DRD2 (0.43) | DRD2SIGMAR1EBPTMEM97PLAAT3 | |
| SCHEMBL6049246 | 0.77 | STAT3 (0.57) | TRPV1DRD2 | |
| SCHEMBL6049410 | 0.76 | ADRB2 (0.53) | DRD2 | |
| SCHEMBL10776111 | 0.76 | STAT3 (0.53) | — | |
| SCHEMBL6049316 | 0.76 | DRD2 (0.61) | DRD2 | |
| SCHEMBL6049319 | 0.75 | KMT2A (0.47) | PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL12040575 | 0.73 | EBP (0.67) | SIGMAR1EBPTMEM97PLAAT3PLAAT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311477-A4 | NOVEL THIOCARBAMIC ACID DERIVATIVES AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | PACIFIC CORP (KR) | 2005-01-12 | — | — | EP | disclosed |
| EP-1311477-A1 | NOVEL THIOCARBAMIC ACID DERIVATIVES AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | PACIFIC CORPORATION (KR) | 2003-05-21 | — | — | EP | disclosed |
| WO-2002016317-A1 | NOVEL THIOCARBAMIC ACID DERIVATIVES AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME | PACIFIC CORPORATION (KR) | 2002-02-28 | — | — | WO | disclosed |