Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAAT3 | P53816 | 1/20 | 0.42 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.42 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.42 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | EBP | Q15125 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6139009 | 0.85 | TRPV1 (0.43) | PLAAT3PLAAT5PLAAT2PLAAT4DRD2 | |
| SCHEMBL6049293 | 0.80 | DRD2 (0.43) | DRD2POLBGAAEBPSIGMAR1 | |
| SCHEMBL6049316 | 0.78 | DRD2 (0.61) | DRD2POLB | |
| SCHEMBL6140314 | 0.78 | DRD2 (0.47) | PLAAT3PLAAT5PLAAT2PLAAT4DRD2 | |
| SCHEMBL6049319 | 0.77 | KMT2A (0.47) | PLAAT3PLAAT5PLAAT2PLAAT4POLB | |
| SCHEMBL6049294 | 0.76 | DRD2 (0.43) | PLAAT3PLAAT5PLAAT2PLAAT4DRD2 | |
| SCHEMBL6049246 | 0.75 | STAT3 (0.57) | DRD2POLBGAATRPV1 | |
| SCHEMBL6049410 | 0.75 | ADRB2 (0.53) | DRD2POLBGAA | |
| SCHEMBL6049261 | 0.73 | MEN1 (0.47) | PLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL14420914 | 0.72 | SMN1; SMN2 (0.51) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060264480-A1 | Novel thiocarbamic acid derivatives and the pharmaceutical compositions containing the same | SUH YOUNG G | 2006-11-23 | — | — | US | disclosed |
| US-20030203944-A1 | Novel thiocarbamic acid derivatives and the pharmaceutical compositions containing the same | PACIFIC CORPORATION (KR) | 2003-10-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060264480-A1 | Novel thiocarbamic acid derivatives and the pharmaceutical compositions containing the same | TRPV1, TRPA1, TRPV5 | PLAAT3 4113/4885PLAAT5 1301/4885PLAAT2 2804/4885 |
| US-20030203944-A1 | Novel thiocarbamic acid derivatives and the pharmaceutical compositions containing the same | TRPV1, TRPA1, TRPV5 | PLAAT3 4113/4885PLAAT5 1301/4885PLAAT2 2804/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.