Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.43 |
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | ELOVL1 | Q9BW60 | 2/20 | 0.42 |
| ▸ | ANO1 | Q5XXA6 | 2/20 | 0.40 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6140425 | 0.71 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL6139854 | 0.71 | RAB9A (0.49) | RAB9ANPC1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL6139947 | 0.70 | RAB9A (0.54) | RAB9ANPC1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL19576953 | 0.69 | ALDH1A1 (0.53) | RAB9ANPC1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL22353072 | 0.68 | ALDH1A1 (0.55) | RAB9ANPC1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL28697076 | 0.68 | ELOVL1 (0.52) | RAB9ANPC1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL7157785 | 0.67 | NPC1 (0.58) | RAB9ANPC1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL7150740 | 0.67 | NPC1 (0.57) | RAB9ANPC1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL22352984 | 0.67 | ALDH1A1 (0.59) | RAB9ANPC1SMN1; SMN2LMNAMAPK1 | |
| SCHEMBL7153521 | 0.67 | NPC1 (0.60) | RAB9ANPC1SMN1; SMN2LMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351938-A1 | PHENYL DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-10-15 | — | — | EP | claimed |
| WO-2002057236-A1 | PHENYL DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-07-25 | — | — | WO | claimed |