Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.30 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6139900 | 0.75 | L3MBTL1 (0.36) | — | |
| SCHEMBL27466440 | 0.75 | MAPT (0.39) | — | |
| SCHEMBL28749741 | 0.72 | JAK2 (0.31) | JAK2JAK1 | |
| SCHEMBL3133794 | 0.71 | MMP2 (0.47) | HRH3FFAR4SLC6A3 | |
| SCHEMBL20267018 | 0.68 | OPRL1 (0.54) | HSD11B1HRH3OPRM1OPRD1OPRK1 | |
| SCHEMBL11246572 | 0.66 | HRH3 (0.40) | HRH3OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL20300595 | 0.64 | DRD2 (0.41) | HRH3OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL6482123 | 0.64 | ABAT (0.43) | HRH3OPRM1OPRD1OPRK1OPRL1 | |
| SCHEMBL15524912 | 0.64 | HRH3 (0.41) | HSD11B1HRH3OPRM1OPRD1OPRK1 | |
| SCHEMBL27890202 | 0.64 | ALDH5A1 (0.43) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1196403-B1 | ANTIPSYCHOTIC CYCLIC N-ARALKYL AMINES | SANOFI AVENTIS (FR) | 2005-11-09 | — | — | EP | disclosed |
| US-6908914-B1 | Antipsychotic cyclic N-aralkylamines | SANOFI-SYNTHELABO (FR) | 2005-06-21 | — | — | US | disclosed |