Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.65 |
| ▸ | TDO2 | P48775 | 3/20 | 0.65 |
| ▸ | ACP3 | P15309 | 3/20 | 0.51 |
| ▸ | PNMT | P11086 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | XBP1 | P17861 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28297702 | 0.78 | IDO1 (0.43) | IDO1TDO2TSHR | |
| SCHEMBL9293034 | 0.76 | IDO1 (0.58) | IDO1TDO2ACP3PNMTCES2 | |
| Ammonia Solution, Strong SCHEMBL10334616 | 0.75 | IDO1 (0.57) | IDO1TDO2ACP3PNMTCES2 | |
| SCHEMBL4135655 | 0.74 | PNMT (0.59) | IDO1TDO2ACP3PNMTCES2 | |
| SCHEMBL10334601 | 0.74 | IDO1 (0.56) | IDO1TDO2ACP3PNMTCES2 | |
| SCHEMBL14648282 | 0.74 | IDO1 (0.56) | IDO1TDO2ACP3PNMTCES2 | |
| SCHEMBL10334580 | 0.74 | IDO1 (0.59) | IDO1TDO2ACP3PNMTCES2 | |
| SCHEMBL13357679 | 0.73 | IDO1 (0.59) | IDO1TDO2ACP3PNMTCES2 | |
| SCHEMBL7466690 | 0.73 | IDO1 (0.55) | IDO1TDO2ACP3PNMTCES2 | |
| SCHEMBL23021670 | 0.73 | PNMT (0.57) | IDO1TDO2ACP3PNMTCES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1492757-A1 | (2-((2-ALKOXY)-PHENYL)-CYCLOPENT-1-ENYL) AROMATIC CARBO- AND HETEROCYCLIC CARBOXYLIC ACID AND DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2005-01-05 | — | — | EP | disclosed |
| WO-2003084917-A1 | (2-((2-ALKOXY) -PHENYL) -CYCLOPENT-1-ENYL) AROMATIC CARBO AND HETEROCYCLIC ACID AND DERIVATIVES | GLAXO GROUP LIMITED (GB) | 2003-10-16 | — | — | WO | disclosed |