Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 8/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.60 |
| ▸ | SLC7A5 | Q01650 | 5/20 | 0.60 |
| ▸ | RECQL | P46063 | 4/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.60 |
| ▸ | USP2 | O75604 | 3/20 | 0.60 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.60 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.60 |
| ▸ | HTR2A | P28223 | 2/20 | 0.60 |
| ▸ | EGFR | P00533 | 2/20 | 0.60 |
| ▸ | FYN | P06241 | 2/20 | 0.60 |
| ▸ | LCK | P06239 | 2/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.60 |
| ▸ | ALOX12 | P18054 | 6/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 5/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31613032 | 1.00 | ALOX15 (0.60) | ALOX15KDM4EHSD17B10SLC7A5RECQL | |
| SCHEMBL7262102 | 0.87 | SLC7A5 (0.46) | ALOX15KDM4EHSD17B10SLC7A5RECQL | |
| SCHEMBL7266117 | 0.87 | THRB (0.49) | ALOX15KDM4EHSD17B10SLC7A5RECQL | |
| SCHEMBL9995880 | 0.86 | FOS (0.55) | ALOX15KDM4EHSD17B10SLC7A5RECQL | |
| SCHEMBL13209180 | 0.85 | ALOX15 (0.54) | ALOX15KDM4EHSD17B10SLC7A5RECQL | |
| Hydrochloric Acid SCHEMBL7261419 | 0.85 | SLC7A5 (0.49) | ALOX15KDM4EHSD17B10SLC7A5RECQL | |
| SCHEMBL630703 | 0.83 | SLC7A5 (0.57) | SLC7A5BLMESR1SLC6A2 | |
| Melevodopa SCHEMBL34004 | 0.83 | ALOX15 (0.66) | ALOX15KDM4EHSD17B10SLC7A5RECQL | |
| Melevodopa SCHEMBL8470037 | 0.83 | ALOX15 (0.66) | ALOX15KDM4EHSD17B10SLC7A5RECQL | |
| SCHEMBL594571 | 0.83 | SLC7A5 (0.57) | SLC7A5BLMESR1SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1646480-A | Derivatives of hydroxyphenyl, a method for preparing thereof and their pharmaceutical composition | MOGAM BIOTECH RES INST (KR) | 2005-07-27 | — | — | CN | disclosed |
| EP-1499585-A1 | DERIVATIVES OF HYDROXYPHENYL, A METHOD FOR PREPARING THEREOF AND THEIR PHARMACEUTICAL COMPOSITION | Mogam Biotechnology Research Institute (KR) | 2005-01-26 | — | — | EP | disclosed |
| US-20040082664-A1 | Derivatives of hydroxyphenyl, a method for preparing thereof and their pharmaceutical composition | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2004-04-29 | — | — | US | disclosed |
| WO-2003089405-A1 | DERIVATIVES OF HYDROXYPHENYL, A METHOD FOR PREPARING THEREOF AND THEIR PHARMACEUTICAL COMPOSITION | MOGAM BIOTECHNOLOGY RESEARCH INSTITUTE (KR) | 2003-10-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040082664-A1 | Derivatives of hydroxyphenyl, a method for preparing thereof and their pharmaceutical composition | LCK, SRC, FYN | ALOX15 1529/4885KDM4E 482/4885HSD17B10 549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.