SCHEMBL6141077

SCHEMBL6141077

CCCCCCCCCCCCCCCC(O)C(CO)NC(=O)CCCCCCC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 3/20 1.00
▸ KMT2A Q03164 3/20 1.00
▸ ASAH1 Q13510 1/20 0.75
▸ DEGS1 O15121 2/20 0.74
▸ PLA2G4A P47712 2/20 0.64
▸ CETP P11597 4/20 0.59
▸ THRB P10828 1/20 0.59
▸ FAAH O00519 2/20 0.54
▸ MAPK1 P28482 1/20 0.54
▸ NOD1 Q9Y239 1/20 0.49
▸ PLA2G2C Q5R387 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6658827 1.00 MEN1 (1.00) MEN1KMT2AASAH1DEGS1PLA2G4A
SCHEMBL3190081 1.00 MEN1 (1.00) MEN1KMT2AASAH1DEGS1PLA2G4A
SCHEMBL6662705 1.00 MEN1 (1.00) MEN1KMT2AASAH1DEGS1PLA2G4A
SCHEMBL21660329 1.00 MEN1 (1.00) MEN1KMT2AASAH1DEGS1PLA2G4A
SCHEMBL22910990 1.00 MEN1 (1.00) MEN1KMT2AASAH1DEGS1PLA2G4A
SCHEMBL21581283 1.00 MEN1 (1.00) MEN1KMT2AASAH1DEGS1PLA2G4A
SCHEMBL22911004 1.00 MEN1 (1.00) MEN1KMT2AASAH1DEGS1PLA2G4A
SCHEMBL21581286 1.00 MEN1 (1.00) MEN1KMT2AASAH1DEGS1PLA2G4A
SCHEMBL21428456 1.00 MEN1 (1.00) MEN1KMT2AASAH1DEGS1PLA2G4A
SCHEMBL6242240 1.00 MEN1 (1.00) MEN1KMT2AASAH1DEGS1PLA2G4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020006420-A1 USE OF A 2-AMINO-ALKANE POLYOL AS AGENT FOR TREATING SKIN AGEING SIGNS PHILIPPE MICHEL (FR) 2002-01-17 — — US claimed
US-6184252-B1 2-amino-1,3-alkanediol compositions for inducing/stimulating hair growth and/or retarding hair loss SOCIETE L'OREAL S.A. (FR) 2001-02-06 — — US claimed
EP-1001739-A1 USE OF A 2-AMINO-ALKANE POLYOL AS AGENT FOR TREATING SKIN AGEING SIGNS L'OREAL (FR) 2000-05-24 — — EP claimed
WO-1999007337-A1 USE OF A 2-AMINO-ALKANE POLYOL AS AGENT FOR TREATING SKIN AGEING SIGNS L'OREAL (FR) 1999-02-18 — — WO claimed
EP-0790053-B1 Use of 2-amino-alkane-1,3-diol to reduce hairloss and/or to induce and stimulate hairgrowth OREAL (FR) 1998-10-07 — — EP claimed
EP-0790053-A1 Use of 2-amino-alkane-1,3-diol to reduce hairloss and/or to induce and stimulate hairgrowth L'OREAL (FR) 1997-08-20 — — EP claimed
EP-0722717-B1 Use of ceramids as thickening agents OREAL (FR) 1997-03-19 — — EP claimed
EP-0722717-A1 Use of ceramids as thickening agents L'OREAL (FR) 1996-07-24 — — EP claimed
JP-9227343-A — — None — — JP disclosed
US-20050271692-A1 Topical cosmetic compositions COSMECEUTIC SOLUTIONS PTY. LTD. 2005-12-08 — — US disclosed
EP-1534214-A1 TOPICAL COSMETIC COMPOSITIONS Cosmeceutic Solutions Pty Ltd (AU) 2005-06-01 — — EP disclosed
WO-2004000242-A1 TOPICAL COSMETIC COMPOSITIONS COSMECEUTIC SOLUTIONS PTY LTD (AU) 2003-12-31 — — WO disclosed
EP-1354870-A1 DIHYDROCERAMIDE DESATURASE INHIBITORS. CONSEJO SUPERIOR DE INVESTIGACIONES CIENTIFICAS (ES) 2003-10-22 — — EP disclosed
US-20020006420-A1 USE OF A 2-AMINO-ALKANE POLYOL AS AGENT FOR TREATING SKIN AGEING SIGNS PHILIPPE MICHEL (FR) 2002-01-17 — — US disclosed
EP-0790053-B1 Use of 2-amino-alkane-1,3-diol to reduce hairloss and/or to induce and stimulate hairgrowth OREAL (FR) 1998-10-07 — — EP disclosed
US-5665699-A Use of ceramides as thickeners L'OREAL (FR) 1997-09-09 — — US disclosed
JP-H09227343-A DEHAIRING RETARDING AND/OR HAIR GROWTH INDUCING AND STIMULATING AGENT CONTAINING 2-AMINO-1,3-ALKANE DIOL L'OREAL SA 1997-09-02 — — JP disclosed
EP-0790053-A1 Use of 2-amino-alkane-1,3-diol to reduce hairloss and/or to induce and stimulate hairgrowth L'OREAL (FR) 1997-08-20 — — EP disclosed
EP-0722717-B1 Use of ceramids as thickening agents OREAL (FR) 1997-03-19 — — EP disclosed
EP-0722717-A1 Use of ceramids as thickening agents L'OREAL (FR) 1996-07-24 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050271692-A1 Topical cosmetic compositions CUTA, MITF, DSG1 MEN1 2207/4885KMT2A 3646/4885ASAH1 16/4885
US-20020006420-A1 USE OF A 2-AMINO-ALKANE POLYOL AS AGENT FOR TREATING SKIN AGEING SIGNS CUTA, GLA, AGER MEN1 4742/4885KMT2A 527/4885ASAH1 274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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