SCHEMBL6141567

SCHEMBL6141567

Nc1ccc(NCc2ccc(O)c(O)c2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ARG1 P05089 1/20 0.73
INSR P06213 3/20 0.59
IGF1R P08069 3/20 0.59
SRC P12931 1/20 0.55
ALPL P05186 1/20 0.50
ALPG P10696 1/20 0.50
PLAA Q9Y263 1/20 0.50
MAPT P10636 4/20 0.48
MAPK1 P28482 4/20 0.48
KDM4E B2RXH2 3/20 0.48
ALDH1A1 P00352 3/20 0.48
ALOX15 P16050 3/20 0.48
HSD17B10 Q99714 3/20 0.48
ADRA2A P08913 2/20 0.48
DRD2 P14416 2/20 0.48
DRD1 P21728 2/20 0.48
DRD4 P21917 2/20 0.48
DRD5 P21918 2/20 0.48
SLC6A2 P23975 2/20 0.48
DRD3 P35462 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL2984845 0.98 ARG1 (0.71) ARG1INSRIGF1RSRCALPL
SCHEMBL2990588 0.88 ARG1 (0.56) ARG1INSRIGF1RSRCMAPT
SCHEMBL10057819 0.85 ARG1 (1.00) ARG1INSRIGF1RSRCALPL
SCHEMBL5154356 0.80 MEN1 (0.50) MAPTMAPK1KDM4EALDH1A1ALOX15
SCHEMBL3422016 0.80 MEN1 (0.50) MAPTMAPK1KDM4EALDH1A1ALOX15
SCHEMBL455536 0.80 MEN1 (0.50) MAPTMAPK1KDM4EALDH1A1ALOX15
SCHEMBL18598523 0.79 MAPT (0.67) ARG1MAPTMAPK1KDM4EALDH1A1
SCHEMBL2475709 0.79 MAPT (0.67) ARG1MAPTMAPK1KDM4EALDH1A1
Hydrochloric Acid SCHEMBL2985269 0.78 MAOA (0.48) MAPTMAPK1KDM4EALDH1A1ALOX15
SCHEMBL31438690 0.78 MAOA (0.48) ARG1MAPTMAPK1KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1493731-A1 N-benzyl-p-phenylenediamine-derivatives containing colouring agents for keratin fibres and these derivatives Wella Aktiengesellschaft (DE) 2005-01-05 EP disclosed