Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 11/20 | 0.44 |
| ▸ | ARG1 | P05089 | 1/20 | 0.41 |
| ▸ | PRKCI | P41743 | 1/20 | 0.40 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | RGS12 | O14924 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | CAMKK2 | Q96RR4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6268483 | 0.89 | ARG1 (0.42) | EGFRARG1PRKCINOX4MAPT | |
| SCHEMBL6266435 | 0.86 | ADRA2B (0.41) | EGFRARG1NOX4MAPTRGS12 | |
| SCHEMBL6272046 | 0.83 | EGFR (0.54) | EGFRMAPTALDH1A1TDP1ADRA2B | |
| SCHEMBL6270750 | 0.83 | CASP1 (0.51) | EGFRARG1PRKCIMAPTALDH1A1 | |
| SCHEMBL2473779 | 0.83 | ADRA2B (0.47) | EGFRMAPTALDH1A1ADRA2BCA12 | |
| SCHEMBL6269748 | 0.83 | BCHE (0.45) | EGFRMAPTALDH1A1TDP1ACHE | |
| Hydrochloric Acid SCHEMBL6269529 | 0.82 | EGFR (0.53) | EGFRMAPTALDH1A1TDP1ADRA2B | |
| Hydrochloric Acid SCHEMBL6269391 | 0.82 | CASP1 (0.50) | EGFRARG1PRKCIMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL6273063 | 0.81 | BCHE (0.44) | EGFRMAPTALDH1A1TDP1ACHE | |
| Hydrochloric Acid SCHEMBL2480911 | 0.81 | ADRA2B (0.46) | EGFRMAPTALDH1A1TDP1ACHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6685751-B2 | SUCH AS 2-((2-AMINO-PHENYLAMINO)-METHYL)-1,4-DIAMINOBENZENE; HAIR DYES | WELLA AKTIENGESELLSCHAFT (DE) | 2004-02-03 | — | — | US | disclosed |
| US-6602302-B1 | Mixtures of carbocyclic amines such as 2-((2-aminophenylamino) -methyl)-1,4-diaminobenzene, couplers and developers, having photostability, wash and colorfastness, used for dyeing human hair | WELLA AG (DE) | 2003-08-05 | — | — | US | disclosed |
| US-20030110578-A1 | Substituted 1,4-diaminobenzene compounds and oxidation dye precursor compositions containing same | WELLA INTERNATIONAL OPERATIONS SWITZERLAND SARL (CH) | 2003-06-19 | — | — | US | disclosed |
| EP-1108708-B1 | 1,4-Diaminobenzene derivatives and colouring agents containing these compounds | WELLA AG (DE) | 2003-01-08 | — | — | EP | disclosed |
| EP-1108708-A1 | 1,4-Diaminobenzene derivatives and colouring agents containing these compounds | Wella Aktiengesellschaft (DE) | 2001-06-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030110578-A1 | Substituted 1,4-diaminobenzene compounds and oxidation dye precursor compositions containing same | KRT18, AOC1, DAO | EGFR 1114/4885ARG1 901/4885PRKCI 2922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.