SCHEMBL6142234

SCHEMBL6142234

Cc1ccc(C)c2c1CC=C2CCC1=CCc2c(C)ccc(C)c21

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9171180 0.85
SCHEMBL28509916 0.77 HTR6 (0.38)
SCHEMBL6277532 0.75 DRD4 (0.32)
SCHEMBL12602249 0.66 HTR7 (0.42)
SCHEMBL2962814 0.64 ALDH1A1 (0.30)
SCHEMBL28491870 0.63 AKT1 (0.42)
SCHEMBL4160455 0.59 ALDH1A1 (0.44)
SCHEMBL3482902 0.59 CYP1A2 (0.33)
SCHEMBL14481407 0.58 CYP1A2 (0.38)
SCHEMBL31598395 0.56 DRD4 (0.42)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0633272-B2 Supported catalysts for the polymerization of olefins BASELL TECHNOLOGY CO BV (NL) 2005-01-12 EP disclosed
US-6774194-B2 POROUS ORGANIC SUPPORT FUNCTIONALISED WITH GROUPS HAVING ACTIVE HYDROGEN ATOMS; ORGANOMETALLIC COMPOUND OF ALUMINIUM CONTAINING O, N OR S HETEROATOMS; IVB, VB OR VIB COMPOUNDS CONTAINING LIGANDS OF THE CYCLOPENTADIENYL TYPE BASELL TECHNOLOGY COMPANY BV (NL) 2004-08-10 US disclosed
US-6664351-B1 Polymerizing using catalyst consisting of reaction product of mixture of racemic and meso isomers of stereorigid metallocene compound of transition metal with two cyclopentadienyl ligands connected by chemical bridge and activating cocatalyst BASELL TECHNOLOGY COMPANY B.V. (NL) 2003-12-16 US disclosed
US-20030134993-A1 Supported catalysts for the polymerization of olefins ALBIZZATI ENRICO (IT) 2003-07-17 US disclosed
EP-0643078-B1 Process for the preparation of ethylene polymers and products obtained therefrom BASELL POLYOLEFINE GMBH (DE) 2003-01-22 EP disclosed
US-6444604-B1 CONTACTING IN INERT SOLVENT FUNCTIONALIZED POROUS ORGANIC SUPPORT AND ORGANOMETALLIC ALUMINUM COMPOUND CONTAINING HETEROATOM, ADDING TRANSITION METAL COMPOUND CONTAINING CYCLOPENTADIENYL LIGAND, RECOVERING SUPPORTED CATALYST BASELL TECHNOLOGY COMPANY BV (NL) 2002-09-03 US disclosed
US-6423660-B1 Supported catalysts for the polymerization of olefins BASELL TECHNOLOGY COMPANY BV (NL) 2002-07-23 US disclosed
EP-0821011-B1 Process for the preparation of ethylene-based polymers BASELL TECHNOLOGY CO BV (NL) 2001-01-31 EP disclosed
US-6136936-A STEREORIGID METALLOCENE MONTELL TECHNOLOGY COMPANY B.V. (NL) 2000-10-24 US disclosed
EP-0575875-B1 Catalysts for the polymerization of olefins MONTELL TECHNOLOGY COMPANY BV (NL) 2000-08-09 EP disclosed
EP-0647243-B1 PROCESS FOR PREPARING AN ETHYLENIC COPOLYMER MONTELL TECHNOLOGY COMPANY BV (NL) 1998-03-18 EP disclosed
EP-0821011-A2 Process for the preparation of ethylene-based polymers and catalyst system used therein Montell Technology Company bv (NL) 1998-01-28 EP disclosed
EP-0633272-B1 Supported catalysts for the polymerization of olefins MONTELL TECHNOLOGY COMPANY BV (NL) 1997-09-17 EP disclosed
US-5585448-A USING CYCLOPENTADIENYL LIGAND CONTAINING METALLOCENE CATALYST MONTELL TECHNOLOGY COMPANY B.V. (NL) 1996-12-17 US disclosed
US-5565533-A SLURRY POLYMERIZATION IN PRESENCE OF A METALLOCENE CATALYST MONTELL TECHNOLOGY COMPANY BV (NL) 1996-10-15 US disclosed
WO-1995035333-A2 ETHYLENE COPOLYMERS, PROCESS FOR THE PREPARATION OF ETHYLENE-BASED POLYMERS AND CATALYST SYSTEM USED THEREIN MONTELL TECHNOLOGY COMPANY B.V. (NL) 1995-12-28 WO disclosed
EP-0643078-A2 Process for the preparation of ethylene polymers and products obtained therefrom Montell Technology Company bv (NL) 1995-03-15 EP disclosed
EP-0633272-A1 Supported catalysts for the polymerization of olefins Montell Technology Company bv (NL) 1995-01-11 EP disclosed
EP-0575875-A2 Catalysts for the polymerization of olefins Montell Technology Company bv (NL) 1993-12-29 EP disclosed
WO-1993025591-A1 PROCESS FOR PREPARING AN ETHYLENIC POLYMER SPHERILENE S.R.L. (IT) 1993-12-23 WO disclosed