Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.31 |
| ▸ | AKT2 | P31751 | 1/20 | 0.31 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2962814 | 0.82 | ALDH1A1 (0.30) | — | |
| SCHEMBL6142234 | 0.75 | — | — | |
| SCHEMBL9171180 | 0.73 | — | — | |
| SCHEMBL21518258 | 0.67 | HTR5A (0.35) | — | |
| SCHEMBL21694427 | 0.67 | ACHE (0.41) | — | |
| SCHEMBL2958875 | 0.64 | ADRA2A (0.31) | — | |
| SCHEMBL4160455 | 0.64 | ALDH1A1 (0.44) | — | |
| SCHEMBL3482902 | 0.64 | CYP1A2 (0.33) | — | |
| SCHEMBL14481407 | 0.62 | CYP1A2 (0.38) | DRD4 | |
| SCHEMBL5029748 | 0.60 | DRD4 (0.42) | DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0537686-B1 | Process for preparing an olefinpolymer by using metallocenes having specially substituted indenylligands | BASELL POLYOLEFINE GMBH (DE) | 2005-01-12 | — | — | EP | disclosed |
| CN-1226882-A | Process for preparing cyclopentadienyl compounds | MONTELL TECHNOLOGY COMPANY BV (NL) | 1999-08-25 | — | — | CN | disclosed |
| EP-0500005-B1 | Process for the preparation of substituted indenes | HOECHST AG (DE) | 1996-02-07 | — | — | EP | disclosed |
| US-5304614-A | Process for the preparation of an olefin polymer using metallocenes having specifically substituted indenyl ligands | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-04-19 | — | — | US | disclosed |
| EP-0537686-A1 | Process for preparing an olefinpolymer by using metallocenes having specially substituted indenylligands | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-04-21 | — | — | EP | disclosed |
| US-5194619-A | PROCESS FOR THE PREPARATION OF SUBSTITUTED INDENES | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-03-16 | — | — | US | disclosed |
| EP-0500005-A1 | Process for the preparation of substituted indenes | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-08-26 | — | — | EP | disclosed |