SCHEMBL6143595

SCHEMBL6143595

CC[C@H](NCC(C)C)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.42
ALDH1A1 P00352 3/20 0.42
KDM4E B2RXH2 1/20 0.42
HPGD P15428 1/20 0.42
TSHR P16473 1/20 0.42
HSD17B10 Q99714 1/20 0.42
TAAR1 Q96RJ0 1/20 0.42
AOC3 Q16853 1/20 0.42
APAF1 O14727 1/20 0.41
CYP3A4 P08684 2/20 0.40
CHRM2 P08172 1/20 0.40
HTR1A P08908 1/20 0.40
ADRA2A P08913 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
CHRM1 P11229 1/20 0.40
SMPD1 P17405 1/20 0.40
DRD1 P21728 1/20 0.40
TBXA2R P21731 1/20 0.40
SLC6A2 P23975 1/20 0.40
SLC6A4 P31645 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21799526 0.82 TAAR1 (0.50) LMNAALDH1A1TAAR1AOC3APAF1
SCHEMBL13970878 0.81 LMNA (0.46) LMNAALDH1A1KDM4EHPGDTSHR
SCHEMBL12228438 0.81 LMNA (0.46) LMNAALDH1A1KDM4EHPGDTSHR
SCHEMBL476492 0.81 LMNA (0.46) LMNAALDH1A1KDM4EHPGDTSHR
SCHEMBL23374780 0.79 TRPA1 (0.47) LMNAALDH1A1KDM4ETAAR1AOC3
SCHEMBL7412823 0.79 CYP3A4 (0.41) LMNAALDH1A1TSHRTAAR1AOC3
Hydrochloric Acid SCHEMBL20446671 0.79 LMNA (0.45) LMNAALDH1A1KDM4EHPGDTSHR
SCHEMBL2847032 0.78 LMNA (0.52) LMNAALDH1A1KDM4EHPGDTSHR
SCHEMBL10426294 0.78 HTT (0.50) LMNAKDM4EHPGDCYP2D6MEN1
SCHEMBL13911223 0.78 SIGMAR1 (0.48) LMNAALDH1A1KDM4EHPGDTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1577294-A1 S-SUBSTITUTED N-1- (HETERO)ARYL ALKYL-N - (HETERO)ARYL ALKYLYSOTHIOCARBAMIDES, METHOD FOR THE PRODUCTION THEREOF, PHYSIOLOGICALLY ACTIVE S-SUBSTITUTED N-1- (HETERO )ARYL ALKYL-N - (HETERO)ARYL ALKYLYSOTHIOCARBAMIDES,A PHARMACEUTICAL COMPOUND AND CURING METHOD Institut Fiziologicheski Aktivnykh Veschestv Rossiyskov Akademii Nauk (RU) 2005-09-21 EP disclosed