Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ASPH | Q12797 | 1/20 | 0.40 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.40 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13970878 | 1.00 | LMNA (0.46) | LMNATSHRKDM4EALDH1A1HPGD | |
| SCHEMBL12228438 | 1.00 | LMNA (0.46) | LMNATSHRKDM4EALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL20446671 | 0.98 | LMNA (0.45) | LMNATSHRKDM4EALDH1A1HPGD | |
| SCHEMBL2847032 | 0.83 | LMNA (0.52) | LMNATSHRKDM4EALDH1A1HPGD | |
| SCHEMBL13911223 | 0.83 | SIGMAR1 (0.48) | LMNATSHRKDM4EALDH1A1HPGD | |
| SCHEMBL10282547 | 0.83 | RIPK1 (0.51) | LMNASIGMAR1MTORRAB9AGRM7 | |
| SCHEMBL11622496 | 0.83 | TAAR1 (0.48) | SIGMAR1MTORRAB9AGRM7 | |
| SCHEMBL13520315 | 0.83 | RIPK1 (0.51) | LMNASIGMAR1MTORRAB9AGRM7 | |
| SCHEMBL20817230 | 0.83 | SIGMAR1 (0.47) | LMNATSHRKDM4EALDH1A1HPGD | |
| SCHEMBL13051383 | 0.83 | HTT (0.49) | LMNATSHRALDH1A1SIGMAR1MTOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9982015-B2 | Cyclin based inhibitors of CDK2 and CDK4 | UNIVERSITY OF SOUTH CAROLINA (US) | 2018-05-29 | — | — | US | claimed |
| US-20170218018-A1 | CYCLIN BASED INHIBITORS OF CDK2 AND CDK4 | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-08-03 | — | — | US | claimed |
| US-20230159475-A1 | COMPOUNDS WITH IMMUNOMODULATORY ACTIVITY AND THERAPEUTIC USES THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2023-05-25 | — | — | US | disclosed |
| WO-2022058809-A1 | MULTILAYER POLYMERIC MATRIX | UNIVERSIDAD DE LOS ANDES (CO) | 2022-03-24 | — | — | WO | disclosed |
| US-10016394-B2 | PPARG modulators for treatment of osteoporosis | THE SCRIPPS RESEARCH INSTITUTE (US) | 2018-07-10 | — | — | US | disclosed |
| US-9982015-B2 | Cyclin based inhibitors of CDK2 and CDK4 | UNIVERSITY OF SOUTH CAROLINA (US) | 2018-05-29 | — | — | US | disclosed |
| US-20170218018-A1 | CYCLIN BASED INHIBITORS OF CDK2 AND CDK4 | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2017-08-03 | — | — | US | disclosed |
| US-20170035730-A1 | PPARG MODULATORS FOR TREATMENT OF OSTEOPOROSIS | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED | 2017-02-09 | — | — | US | disclosed |
| US-9376465-B2 | Cyclin based inhibitors of CDK2 and CDK4 | UNIVERSITY OF SOUTH CAROLINA (US) | 2016-06-28 | — | — | US | disclosed |
| US-20150011730-A1 | Cyclin Based Inhibitors of CDK2 and CDK4 | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-01-08 | — | — | US | disclosed |
| US-20140296484-A1 | Cyclin Based Inhibitors of CDK2 and CDK4 | UNIVERSITY OF SOUTH CAROLINA (US) | 2014-10-02 | — | — | US | disclosed |
| EP-2410842-A1 | SANITIZER FORMULATIONS | Arch Chemicals, Inc. (US) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010111155-A1 | SANITIZER FORMULATIONS | ARCH CHEMICALS, INC. (US) | 2010-09-30 | — | — | WO | disclosed |
| US-7482359-B2 | Androgen receptor modulators | MERCK & CO., INC. (US) | 2009-01-27 | — | — | US | disclosed |
| US-20050008607-A1 | Composition containing a carbonyl amine | L'OREAL (FR) | 2005-01-13 | — | — | US | disclosed |
| EP-0711278-A1 | 2-(2-HYDROXYPHENYL)-5-(N-PHENYLMETHYL-AMINOMETHYL)-PYRROLES AS ANTIPSYCHOTIC AGENTS | SMITHKLINE BEECHAM PLC (GB) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004037-A1 | 2-(2-HYDROXYPHENYL)-5-(N-PHENYLMETHYL-AMINOMETHYL)-PYRROLES AS ANTIPSYCHOTIC AGENTS | SMITHKLINE BEECHAM PLC (GB) | 1995-02-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150011730-A1 | Cyclin Based Inhibitors of CDK2 and CDK4 | CDK4, CDK2, CDK8 | LMNA 1848/4885TSHR 1652/4885KDM4E 4044/4885 |
| US-20170035730-A1 | PPARG MODULATORS FOR TREATMENT OF OSTEOPOROSIS | PPARG, PPARA, PPARD | LMNA 2152/4885TSHR 98/4885KDM4E 1844/4885 |
| US-20050008607-A1 | Composition containing a carbonyl amine | CUTA, COL14A1, MAOA | LMNA 352/4885TSHR 4069/4885KDM4E 237/4885 |
| US-10016394-B2 | PPARG modulators for treatment of osteoporosis | PPARG, PPARA, PPARD | LMNA 2152/4885TSHR 98/4885KDM4E 1844/4885 |
| US-20170218018-A1 | CYCLIN BASED INHIBITORS OF CDK2 AND CDK4 | CDK4, CDK2, CDK8 | LMNA 1848/4885TSHR 1652/4885KDM4E 4044/4885 |
| US-20140296484-A1 | Cyclin Based Inhibitors of CDK2 and CDK4 | CDK4, CDK2, CDK8 | LMNA 1848/4885TSHR 1652/4885KDM4E 4044/4885 |
| US-20230159475-A1 | COMPOUNDS WITH IMMUNOMODULATORY ACTIVITY AND THERAPEUTIC USES THEREOF | CD47, CD74, ICOS | LMNA 4810/4885TSHR 3657/4885KDM4E 2611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.