Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 5/20 | 0.45 |
| ▸ | CA1 | P00915 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.36 |
| ▸ | RARA | P10276 | 2/20 | 0.36 |
| ▸ | RARB | P10826 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31487092 | 1.00 | TP53 (0.46) | TP53LMNACYP3A4HPGDALOX15 | |
| SCHEMBL2308071 | 0.84 | LMNA (0.46) | TP53LMNACYP3A4HPGDALOX15 | |
| SCHEMBL23542397 | 0.83 | LMNA (0.48) | TP53LMNACYP3A4HPGDALOX15 | |
| SCHEMBL1054064 | 0.82 | HIF1A (0.50) | TP53LMNACYP3A4HPGDALOX15 | |
| SCHEMBL10906475 | 0.78 | CA2 (0.56) | LMNAALOX15CA2CA1ALDH1A1 | |
| SCHEMBL2955217 | 0.78 | CA2 (0.43) | TP53LMNACYP3A4HPGDALOX15 | |
| SCHEMBL28474445 | 0.78 | LMNA (0.38) | TP53LMNACYP3A4HPGDALOX15 | |
| SCHEMBL9510317 | 0.77 | CA2 (0.38) | CA2CA1ALDH1A1GAAGABRA1 | |
| SCHEMBL5587534 | 0.76 | ALOX15 (0.55) | TP53LMNACYP3A4HPGDALOX15 | |
| SCHEMBL22090225 | 0.76 | CYP3A4 (0.46) | TP53LMNACYP3A4HPGDALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129521-B2 | One pot synthesis of tetrazole derivatives of rapamycin | ABBOTT LABORATORIES (US) | 2012-03-06 | — | — | US | claimed |
| WO-2006078123-A1 | POLYMERIZATION INHIBITOR FOR 1,3-BUTADIENE AND A METHOD OF INHIBITING POLYMERIZATION OF 1,3-BUTADIENE BY IMPUTING THEREOF | YEOCHUN NCC CO., LTD. (KR) | 2006-07-27 | — | — | WO | claimed |
| EP-2426098-B1 | PROCESS FOR PRODUCING POLYHYDRIC PHENOL | MITSUI CHEMICALS INC (JP) | 2015-01-21 | — | — | EP | disclosed |
| US-20070032581-A1 | Additive mixtures | CIBA CORPORATION | 2007-02-08 | — | — | US | disclosed |
| WO-2006078123-A1 | POLYMERIZATION INHIBITOR FOR 1,3-BUTADIENE AND A METHOD OF INHIBITING POLYMERIZATION OF 1,3-BUTADIENE BY IMPUTING THEREOF | YEOCHUN NCC CO., LTD. (KR) | 2006-07-27 | — | — | WO | disclosed |
| US-20050197433-A1 | Molecular weight modification of thermoplastic polymers | CIBA SPECIALTY CHEMICALS CORP. | 2005-09-08 | — | — | US | disclosed |
| EP-0323086-B1 | Process for preparing detergents | EXXON CHEMICAL PATENTS INC (US) | 1994-06-08 | — | — | EP | disclosed |
| US-5183742-A | Useful for early detection, diagnosis and control of diseases such as diabetes, gastropathy, naphropathy and hepatic insufficiency | DAI NIPPON INSATSU KABUSHIKI KAISHA (JP) | 1993-02-02 | — | — | US | disclosed |
| US-4957642-A | REACTION OF MAGNESIUM COMPOUND AND A PHENOL, FREE OF INORGANIC HALIDE CATALYST | EXXON CHEMICAL PATENTS INC. (US) | 1990-09-18 | — | — | US | disclosed |
| EP-0323086-A2 | Process for preparing detergents | EXXON CHEMICAL PATENTS INC. (US) | 1989-07-05 | — | — | EP | disclosed |
| US-3934056-A | Resin compositions of high adhesivity comprising E/VA copolymer, chlorinated or chlorosulfonated polyethylene, an unsaturated acid and a peroxy compound | SHOWA DENKO KABUSHIKI KAISHA (JA) | 1976-01-20 | — | — | US | disclosed |