SCHEMBL2308071

SCHEMBL2308071

COc1ccc(C(C)(C)C)c(C(C)(C)C)c1O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.46
CYP3A4 P08684 3/20 0.46
HPGD P15428 3/20 0.46
ALOX15 P16050 3/20 0.46
TP53 P04637 2/20 0.46
CA2 P00918 4/20 0.44
CA1 P00915 2/20 0.44
ALDH1A1 P00352 5/20 0.42
MAPT P10636 4/20 0.42
KDM4E B2RXH2 3/20 0.42
MAPK1 P28482 3/20 0.42
HSD17B10 Q99714 3/20 0.42
ALOX12 P18054 1/20 0.42
GAA P10253 1/20 0.41
ERN1 O75460 2/20 0.37
HIF1A Q16665 1/20 0.36
EPAS1 Q99814 1/20 0.36
MCL1 Q07820 1/20 0.36
RARA P10276 1/20 0.36
RARB P10826 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL61454 0.84 TP53 (0.46) LMNACYP3A4HPGDALOX15TP53
SCHEMBL31487092 0.84 TP53 (0.46) LMNACYP3A4HPGDALOX15TP53
SCHEMBL23542397 0.83 LMNA (0.48) LMNACYP3A4HPGDALOX15TP53
SCHEMBL22090225 0.80 CYP3A4 (0.46) LMNACYP3A4HPGDALOX15TP53
SCHEMBL24448846 0.78 LMNA (0.44) LMNACYP3A4HPGDALOX15TP53
SCHEMBL14112778 0.78 LMNA (0.44) LMNACYP3A4HPGDALOX15TP53
SCHEMBL10906475 0.78 CA2 (0.56) LMNAALOX15CA2CA1ALDH1A1
SCHEMBL27199180 0.78 PTGDR2 (0.39) CA2CA1ALDH1A1GAARARA
SCHEMBL23771985 0.78 HPGD (0.38) LMNACYP3A4HPGDALOX15TP53
SCHEMBL7585737 0.76 LMNA (0.37) LMNACYP3A4HPGDALOX15TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7196213-B2 Process for producing phosphate KAO CORPORATION (JP) 2007-03-27 US claimed
US-20060229377-A1 Photopolymerizable single-component crown and bridge material KETTENBACH GMBH & CO. KG 2006-10-12 US claimed
EP-0769016-B1 PROCESS FOR PRODUCING LIGHT-COLOURED SURFACTANTS HENKEL KGAA (DE) 1998-09-30 EP claimed
CN-119241340-A Stable production method of antioxidant butyl hydroxy anisole 南京晶典抗氧化技术研究院有限公司 2025-01-03 CN disclosed
WO-2024203572-A1 COPOLYMER AND CONTACT LENS TREATMENT SOLUTION 日油株式会社 2024-10-03 WO disclosed
CN-114945606-B Polyalkylene glycol mono (meth) acrylate and polymer thereof, and composition for film 日油株式会社 2024-02-27 CN disclosed
CN-117222944-A Resin for photoresist, photoresist and cured product 日油株式会社 2023-12-12 CN disclosed
CN-117136226-A Dispersing agent 日油株式会社 2023-11-28 CN disclosed
WO-2022219994-A1 DISPERSANT 日油株式会社 2022-10-20 WO disclosed
WO-2022215456-A1 PHOTORESIST RESIN, PHOTORESIST, AND CURED PRODUCT 日油株式会社 2022-10-13 WO disclosed
CN-114945606-A Polyalkylene glycol mono (meth) acrylate, polymer thereof, and composition for film 日油株式会社 2022-08-26 CN disclosed
US-20090074844-A1 TRENADERMAL ABSORPTION PREPARATION ONO PHARMACEUTICAL CO., LTD. (JP) 2009-03-19 US disclosed
EP-1878429-A1 TRENADERMAL ABSORPTION PREPARATION Ono Pharmaceutical Co., Ltd. (JP) 2008-01-16 EP disclosed
EP-1433790-B1 Processes for producing and stabilizing phosphates KAO CORP (JP) 2007-04-25 EP disclosed
US-7196213-B2 Process for producing phosphate KAO CORPORATION (JP) 2007-03-27 US disclosed
US-20070066767-A1 Polyalkylene glycols NIPPON SHOKUBAI CO., LTD. (JP) 2007-03-22 US disclosed
US-20060229377-A1 Photopolymerizable single-component crown and bridge material KETTENBACH GMBH & CO. KG 2006-10-12 US disclosed
US-20040186309-A1 Process for producing phosphate KAO CORPORATION (JP) 2004-09-23 US disclosed
EP-1433790-A1 Processes for producing and stabilizing phosphates Kao Corporation (JP) 2004-06-30 EP disclosed
US-3951839-A HYDROXY COMPOUND ANTIOXIDANT, BLEACH KAO SOAP CO., LTD. (JA) 1976-04-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070066767-A1 Polyalkylene glycols PUF60, PARG, DGAT1 LMNA 3285/4885CYP3A4 1910/4885HPGD 930/4885
US-20090074844-A1 TRENADERMAL ABSORPTION PREPARATION SLC10A2, SLC10A1, TREH LMNA 697/4885CYP3A4 433/4885HPGD 364/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.