Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8346348 | 0.83 | PTGS2 (0.69) | PTGS2PTGS1 | |
| SCHEMBL5594051 | 0.79 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL215052 | 0.76 | PTGS2 (1.00) | PTGS2PTGS1 | |
| Sulfamide SCHEMBL4639044 | 0.75 | PTGS2 (0.81) | PTGS2PTGS1 | |
| SCHEMBL7773789 | 0.74 | PTGS2 (0.50) | PTGS2PTGS1 | |
| SCHEMBL8025367 | 0.74 | PTGS2 (0.58) | PTGS2PTGS1 | |
| SCHEMBL8028157 | 0.73 | PTGS2 (0.77) | PTGS2PTGS1 | |
| Benzenesulfonamide SCHEMBL7048970 | 0.72 | PTGS2 (0.62) | PTGS2PTGS1 | |
| SCHEMBL5069859 | 0.71 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL7114451 | 0.71 | PTGS2 (0.80) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575581-A1 | COMBINATIONS OF VALSARTAN WITH COX-2 INHIBITORS | Novartis AG (CH) | 2005-09-21 | — | — | EP | disclosed |
| EP-1443967-A1 | CYCLOOXYGENASE-2 INHIBITOR/HISTONE DEACETYLASE INHIBITOR COMBINATION | Novartis AG (CH) | 2004-08-11 | — | — | EP | disclosed |
| WO-2004054575-A1 | COMBINATIONS OF VALSARTAN WITH COX-2 INHIBITORS | NOVARTIS AG (CH) | 2004-07-01 | — | — | WO | disclosed |
| WO-2003039599-A1 | CYCLOOXYGENASE-2 INHIBITOR/HISTONE DEACETYLASE INHIBITOR COMBINATION | NOVARTIS AG (CH) | 2003-05-15 | — | — | WO | disclosed |