SCHEMBL6150752

SCHEMBL6150752

CCC(=O)Oc1cc(C(=O)c2c(Cl)cccc2Cl)c(C)cc1OC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TUBB4A P04350 1/20 0.40
TUBB P07437 1/20 0.40
TUBA3C P0DPH7 1/20 0.40
TUBA1B P68363 1/20 0.40
TUBA4A P68366 1/20 0.40
TUBB4B P68371 1/20 0.40
TUBB3 Q13509 1/20 0.40
TUBB2A Q13885 1/20 0.40
TUBB8 Q3ZCM7 1/20 0.40
TUBA3E Q6PEY2 1/20 0.40
TUBA1A Q71U36 1/20 0.40
TUBA1C Q9BQE3 1/20 0.40
TUBB6 Q9BUF5 1/20 0.40
TUBB2B Q9BVA1 1/20 0.40
TUBB1 Q9H4B7 1/20 0.40
RORC P51449 2/20 0.40
CES2 O00748 1/20 0.40
CES1 P23141 1/20 0.40
LMNA P02545 2/20 0.39
NPC1 O15118 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6150594 0.88 CES2 (0.48) RORCCES2CES1LMNANPC1
SCHEMBL8463397 0.85 TSHR (0.45) RORCCES2CES1LMNANPC1
SCHEMBL8466816 0.84 RORC (0.42) RORCCES2CES1LMNANPC1
SCHEMBL6307594 0.83 CES2 (0.46) RORCCES2CES1LMNANPC1
SCHEMBL8463650 0.83 PDE4B (0.43) RORCCES2CES1LMNANPC1
SCHEMBL8466332 0.82 RORC (0.42) RORCCES2CES1LMNANPC1
SCHEMBL8466614 0.82 PDE4B (0.44) RORCCES2CES1LMNARAB9A
SCHEMBL8466199 0.82 PDE4B (0.45) RORCCES2CES1NPC1RAB9A
SCHEMBL6149650 0.81 RORC (0.41) RORCCES2CES1LMNANPC1
SCHEMBL7602573 0.81 TAS1R3 (0.41) RORCCES2CES1LMNARAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0727141-B1 Fungicidal methods, compounds and compositions containing benzophenones BASF AG (DE) 2005-11-02 EP disclosed
US-5922919-A Fungicidal methods, compounds and compositions containing benzophenones AMERICAN CYANAMID COMPANY (US) 1999-07-13 US disclosed
US-5866722-A Fungicidal methods compounds and compositions containing benzophenones AMERICAN CYANAMID COMPANY (US) 1999-02-02 US disclosed
US-5773663-A FOR CONTROL OF PHYTOPATHOGENIC FUNGI IN CROPS AMERICAN CYANAMID COMPANY (US) 1998-06-30 US disclosed
EP-0727141-A2 Fungicidal methods, compounds and compositions containing benzophenones American Cyanamid Company (US) 1996-08-21 EP disclosed