Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 2/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23174784 | 1.00 | TSHR (0.66) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL16286524 | 1.00 | TSHR (0.66) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL80819 | 0.98 | TSHR (0.62) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL139742 | 0.93 | TSHR (0.59) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL28074744 | 0.91 | TSHR (0.57) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL6440674 | 0.88 | TSHR (0.50) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL108693 | 0.85 | TSHR (0.52) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL8639379 | 0.84 | TSHR (0.46) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL27152282 | 0.84 | TSHR (0.45) | TSHRALDH1A1CYP3A4HPGDTP53 | |
| SCHEMBL16286758 | 0.83 | TSHR (0.61) | TSHRALDH1A1CYP3A4HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3310792-B1 | PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE | DOW SILICONES CORP (US) | 2021-07-21 | — | — | EP | claimed |
| EP-3310792-B1 | PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE | DOW SILICONES CORP (US) | 2021-07-21 | — | — | EP | disclosed |
| EP-3310793-B1 | PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE | DOW SILICONES CORP (US) | 2021-06-09 | — | — | EP | disclosed |
| US-10273254-B2 | Process for preparing an acryloyloxysilane | DOW CORNING CORPORATION (US) | 2019-04-30 | — | — | US | disclosed |
| US-10246473-B2 | Process for preparing an acryloyloxysilane | DOW CORNING CORPORATION (US) | 2019-04-02 | — | — | US | disclosed |
| EP-2785726-B1 | ESTER-FUNCTIONAL SILANES AND THE PREPARATION AND USE THEREOF; AND USE OF IMINIUM COMPOUNDS AS PHASE TRANSFER CATALYSTS | DOW SILICONES CORP (US) | 2018-08-01 | — | — | EP | disclosed |
| US-20180155371-A1 | PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE | DOW SILICONES CORPORATION | 2018-06-07 | — | — | US | disclosed |
| US-20180134734-A1 | PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE | DOW SILICONES CORPORATION | 2018-05-17 | — | — | US | disclosed |
| US-9518072-B2 | Ester-functional silanes and the preparation and use thereof; and use of iminium compounds as phase transfer catalysts | DOW CORNING CORPORATION (US) | 2016-12-13 | — | — | US | disclosed |
| EP-2762482-B1 | PROCESS FOR PURIFYING AN ACRYLOYLOXYSILANE | DOW CORNING (US) | 2016-10-26 | — | — | EP | disclosed |
| US-9249164-B2 | Process for preparing an acryloyloxysilane | DOW SILICONES CORPORATION | 2016-02-02 | — | — | US | disclosed |
| US-20150126676-A1 | Ester-Functional Silanes And The Preparation And Use Thereof; And Use Of Iminium Compounds As Phase Transfer Catalysts | DOW SILICONES CORPORATION | 2015-05-07 | — | — | US | disclosed |
| EP-2621936-B1 | PROCESS FOR PREPARING AN ACRYLOYLOXYSILANE | DOW CORNING (US) | 2014-10-22 | — | — | EP | disclosed |
| US-20130184482-A1 | Process For Preparing An Acryloyloxysilane | DOW CORNING CORPORATION (US) | 2013-07-18 | — | — | US | disclosed |
| EP-1234830-B1 | Method of preparing an organosilicon compound containing a methacryloxy functional group | DOW CORNING TORAY SILICONE (JP) | 2005-01-19 | — | — | EP | disclosed |
| US-6448427-B1 | REACTING AN ALKALI-METAL SALT OF (METH)ACRYLIC ACID WITH A HALOGEN SUBSTITUTED ORGANOSILICON COMPOUND IN THE PRESENCE OF A TERTIARY AMINE DIAZABICYCLO DERIVATIVE | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 2002-09-10 | — | — | US | disclosed |
| EP-1234830-A2 | Method of preparing an organosilicon compound containing a methacryloxy functional group | Dow Corning Toray Silicone Co., Ltd. (JP) | 2002-08-28 | — | — | EP | disclosed |
| US-20020115878-A1 | METHOD OF PREPARING AN ORGANOSILICON COMPOUND CONTAINING A METHACRYLOXY FUNCTIONAL GROUP | DOW TORAY CO., LTD. (JP) | 2002-08-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150126676-A1 | Ester-Functional Silanes And The Preparation And Use Thereof; And Use Of Iminium Compounds As Phase Transfer Catalysts | ICMT, INTS9, HDHD5 | TSHR 4158/4885ALDH1A1 2430/4885CYP3A4 195/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.