SCHEMBL139742

SCHEMBL139742

C=CC(=O)OCCC[SiH](OC)OC

nearest known ligand 0.59

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.59
ALDH1A1 P00352 4/20 0.59
CYP3A4 P08684 2/20 0.59
HPGD P15428 1/20 0.58
TP53 P04637 3/20 0.48
HIF1A Q16665 3/20 0.48
HSD17B10 Q99714 1/20 0.48
THRB P10828 2/20 0.41
ATM Q13315 1/20 0.38
MAPK1 P28482 1/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HCAR2 Q8TDS4 3/20 0.34
MAPT P10636 1/20 0.30
RAB9A P51151 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28074744 0.98 TSHR (0.57) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL80819 0.95 TSHR (0.62) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL6151225 0.93 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL16286524 0.93 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL23174784 0.93 TSHR (0.66) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL108693 0.89 TSHR (0.52) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL28044492 0.88 TSHR (0.50) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL6440674 0.85 TSHR (0.50) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL7525910 0.84 TSHR (0.57) TSHRALDH1A1CYP3A4HPGDTP53
SCHEMBL7718673 0.83 TSHR (0.42) TSHRALDH1A1CYP3A4HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1242 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117304755-B Powdery interfacial agent prepared from tertiary vinegar redispersible emulsion powder and preparation method thereof 江苏福吉利亚建材有限公司 2026-05-19 CN claimed
EP-4719751-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2026-04-08 EP claimed
WO-2025084741-A1 POLYOLEFIN GRAFT COPOLYMER PRODUCED USING INITIATOR CONTAINING AZIDOFORMATE GROUP AND PRODUCTION METHOD THEREFOR 세종대학교산학협력단 2025-04-24 WO claimed
CN-119350985-A Acrylic ester modified polyurethane hot melt adhesive and preparation method and application thereof 韦尔通科技股份有限公司 2025-01-24 CN claimed
US-20240399627-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC (CH) 2024-12-05 US claimed
WO-2024246819-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC. (CH) 2024-12-05 WO claimed
CN-115772379-B UV delayed-curing double-component polyurethane adhesive and preparation method thereof 韦尔通科技股份有限公司 2024-08-09 CN claimed
CN-117304755-A Powdery interfacial agent prepared from tertiary vinegar redispersible emulsion powder and preparation method thereof 江苏福吉利亚建材有限公司 2023-12-29 CN claimed
US-11834429-B2 Monoethylenically unsaturated monomers and uses thereof BOSTIK SA (FR) 2023-12-05 US claimed
US-20210179576-A1 MONOETHYLENICALLY UNSATURATED MONOMERS AND USES THEREOF UNIVERSITE DE RENNES (FR) 2021-06-17 US claimed
EP-1149075-A1 SYNTHESIS OF DITHIOESTER CHAIN TRANSFER AGENTS AND USE OF BIS(THIOACYL) DISULFIDES OR DITHIOESTERS AS CHAIN TRANSFER AGENTS E.I. DU PONT DE NEMOURS AND COMPANY (US) 2001-10-31 EP claimed
US-6291620-B1 Polymer synthesis E. I. DU PONT DE NEMOURS AND COMPANY 2001-09-18 US claimed
EP-0791016-B1 POLYMER SYNTHESIS DU PONT (US) 2000-07-12 EP claimed
WO-1999005099-A1 SYNTHESIS OF DITHIOESTER CHAIN TRANSFER AGENTS AND USE OF BIS(THIOACYL) DISULFIDES OR DITHIOESTERS AS CHAIN TRANSFER AGENTS COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION (AU) 1999-02-04 WO claimed
EP-0772636-A4 RADIATION- AND/OR MOISTURE-CURABLE SILICONE COMPOSITIONS LOCTITE CORP (US) 1997-09-24 EP claimed
EP-0791016-A1 POLYMER SYNTHESIS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-08-27 EP claimed
EP-0772636-A1 RADIATION- AND/OR MOISTURE-CURABLE SILICONE COMPOSITIONS LOCTITE CORPORATION (US) 1997-05-14 EP claimed
WO-1996015157-A1 POLYMER SYNTHESIS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-05-23 WO claimed
US-5516812-A UV-moisture dual cure silicone conformal coating compositions with improved surface tack LOCTITE CORPORATION (US) 1996-05-14 US claimed
WO-1996002579-A1 RADIATION- AND/OR MOISTURE-CURABLE SILICONE COMPOSITIONS LOCTITE CORPORATION (US) 1996-02-01 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11834429-B2 Monoethylenically unsaturated monomers and uses thereof MEP1A, MEP1B, ALOX5 TSHR 4885/4885ALDH1A1 581/4885CYP3A4 1457/4885
US-20210179576-A1 MONOETHYLENICALLY UNSATURATED MONOMERS AND USES THEREOF MEP1A, MEP1B, ALOX5 TSHR 4885/4885ALDH1A1 581/4885CYP3A4 1457/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.