Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.47 |
| ▸ | BCAT2 | O15382 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | BACE1 | P56817 | 2/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.35 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.35 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29395257 | 0.80 | PARP1 (0.46) | PARP1BCAT2LMNAMAPTTDP1 | |
| SCHEMBL27645536 | 0.76 | BCAT2 (0.43) | PARP1BCAT2LMNAMAPTTDP1 | |
| SCHEMBL15380745 | 0.69 | PARP1 (0.46) | PARP1BCAT2LMNAMAPTTDP1 | |
| Carbamic Acid SCHEMBL29581535 | 0.68 | BCAT2 (0.67) | PARP1BCAT2LMNAMAPTTDP1 | |
| Carbamic Acid SCHEMBL27551243 | 0.68 | BCAT2 (0.67) | PARP1BCAT2LMNAMAPTTDP1 | |
| Urea SCHEMBL1953346 | 0.68 | BCAT2 (0.67) | PARP1BCAT2LMNAMAPTTDP1 | |
| SCHEMBL28045914 | 0.68 | BCAT2 (0.42) | PARP1BCAT2LMNAMAPTKDM4E | |
| SCHEMBL9458564 | 0.66 | ALDH1A1 (0.49) | LMNAKDM4ENPC1KMT2ABACE1 | |
| SCHEMBL28856325 | 0.66 | BACE1 (0.36) | MAPTKDM4ENPC1BACE1HSD17B10 | |
| SCHEMBL6842022 | 0.66 | BCAT2 (0.63) | PARP1BCAT2LMNAMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1753668-A | 1, 5-diaryl pyrrole-3-carboxamide derivatives and their use as cannabinoid receptor modulators | ASTRAZENECA AB (SE) | 2006-03-29 | — | — | CN | claimed |
| CN-113943242-B | Preparation method of polysubstituted pyrrole compound | 浙江工业大学 | 2023-08-15 | — | — | CN | disclosed |
| CN-113943242-A | Preparation method of polysubstituted pyrrole compound | 浙江工业大学 | 2022-01-18 | — | — | CN | disclosed |
| CN-1753668-A | 1, 5-diaryl pyrrole-3-carboxamide derivatives and their use as cannabinoid receptor modulators | ASTRAZENECA AB (SE) | 2006-03-29 | — | — | CN | disclosed |
| EP-1592404-A1 | AQUEOUS DISPERSION COMPRISING STABLE NANOPARTICLES OF A WATER-INSOLUBLE PYRROLE CARBOXAMIDE AND AN EXCIPIENT LIKE MIDDLE CHAIN TRIGLYCERIDES | AstraZeneca AB (SE) | 2005-11-09 | — | — | EP | disclosed |
| WO-2004069227-A1 | AQUEOUS DISPERSION COMPRISING STABLE NANOPARTICLES OF A WATER-INSOLUBLE PYRROLE CARBOXAMIDE AND EXCIPIENT LIKE MIDDLE CHAIN TRIGLYCERIDES | ASTRAZENECA AB (SE) | 2004-08-19 | — | — | WO | disclosed |