Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 2/20 | 0.62 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.62 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 5/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | SLC25A1 | P53007 | 1/20 | 0.55 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.49 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10615498 | 0.85 | CRHBP (0.67) | CRHBPCRHR2FFAR4MAPTALDH1A1 | |
| SCHEMBL6151793 | 0.82 | FFAR4 (0.60) | CRHBPCRHR2FFAR4MAPTALDH1A1 | |
| SCHEMBL28711028 | 0.81 | ALDH1A1 (0.70) | CRHBPCRHR2FFAR4MAPTALDH1A1 | |
| SCHEMBL29978640 | 0.77 | HSD17B2 (0.67) | CRHBPCRHR2FFAR4ALDH1A1HPGD | |
| SCHEMBL29507647 | 0.77 | MAPT (0.69) | CRHBPCRHR2FFAR4MAPTALDH1A1 | |
| SCHEMBL28701969 | 0.77 | ALDH1A1 (0.64) | CRHBPCRHR2FFAR4MAPTALDH1A1 | |
| SCHEMBL1138740 | 0.77 | MAPT (0.69) | CRHBPCRHR2FFAR4MAPTALDH1A1 | |
| SCHEMBL10618991 | 0.77 | FFAR4 (1.00) | FFAR4MAPTALDH1A1LMNAHTT | |
| SCHEMBL8309888 | 0.77 | CRHBP (1.00) | CRHBPCRHR2MAPTALDH1A1DNMT1 | |
| SCHEMBL11056416 | 0.77 | CRHBP (0.71) | CRHBPCRHR2FFAR4MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1018508-B1 | Cationic monobenzenic nitrophenylene diamines, their use for dyeing keratinic fibres, dye compositions containing them and dye processes | OREAL (FR) | 2005-05-04 | — | — | EP | disclosed |
| US-6464731-B1 | 1-(3-(4-AMINO-2-CHLORO-5-NITROPHENYLAMINO)PROPYL)-3-METHYL-3H -IMIDAZOL-1-IUM BROMIDE USED AS DIRECT HAIR DYES; SOLUBILITY AND PHOTOSTABILITY | L'OREAL S.A. (FR) | 2002-10-15 | — | — | US | disclosed |
| EP-1018508-A1 | Cationic monobenzenic nitrophenylene diamines, their use for dyeing keratinic fibres, dye compositions containing them and dye processes | L'OREAL (FR) | 2000-07-12 | — | — | EP | disclosed |
| US-4419101-A | Chlorine-substituted nitro-para-phenylenediamines, a process for their preparation and their use in dyeing keratin fibres | L'OREAL (FR) | 1983-12-06 | — | — | US | disclosed |