Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | CRHBP | P24387 | 2/20 | 0.51 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.51 |
| ▸ | CCR2 | P41597 | 5/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SLC25A1 | P53007 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6151853 | 0.82 | CRHBP (0.62) | FFAR4ALDH1A1MAPTCRHBPCRHR2 | |
| SCHEMBL6151145 | 0.75 | ALDH1A1 (0.55) | FFAR4ALDH1A1MAPTCRHBPCRHR2 | |
| SCHEMBL10618991 | 0.75 | FFAR4 (1.00) | FFAR4ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL30561863 | 0.73 | ALDH1A1 (0.66) | FFAR4ALDH1A1MAPTSMN1; SMN2CRHBP | |
| SCHEMBL2003165 | 0.73 | ALDH1A1 (0.66) | FFAR4ALDH1A1MAPTSMN1; SMN2CRHBP | |
| SCHEMBL7897512 | 0.73 | CRHBP (0.68) | FFAR4ALDH1A1MAPTSMN1; SMN2CRHBP | |
| SCHEMBL11056165 | 0.72 | MAPT (0.50) | FFAR4ALDH1A1MAPTSMN1; SMN2CRHBP | |
| SCHEMBL11056416 | 0.72 | CRHBP (0.71) | FFAR4ALDH1A1MAPTSMN1; SMN2CRHBP | |
| SCHEMBL2006238 | 0.72 | MAPT (0.72) | FFAR4ALDH1A1MAPTSMN1; SMN2CRHBP | |
| SCHEMBL30557374 | 0.72 | MAPT (0.72) | FFAR4ALDH1A1MAPTSMN1; SMN2CRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1018508-B1 | Cationic monobenzenic nitrophenylene diamines, their use for dyeing keratinic fibres, dye compositions containing them and dye processes | OREAL (FR) | 2005-05-04 | — | — | EP | disclosed |
| US-6464731-B1 | 1-(3-(4-AMINO-2-CHLORO-5-NITROPHENYLAMINO)PROPYL)-3-METHYL-3H -IMIDAZOL-1-IUM BROMIDE USED AS DIRECT HAIR DYES; SOLUBILITY AND PHOTOSTABILITY | L'OREAL S.A. (FR) | 2002-10-15 | — | — | US | disclosed |
| EP-1018508-A1 | Cationic monobenzenic nitrophenylene diamines, their use for dyeing keratinic fibres, dye compositions containing them and dye processes | L'OREAL (FR) | 2000-07-12 | — | — | EP | disclosed |