Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 2/20 | 0.67 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | SLC25A1 | P53007 | 1/20 | 0.58 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.55 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | VCAM1 | P19320 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28711028 | 0.90 | ALDH1A1 (0.70) | CRHBPCRHR2ALDH1A1MAPTSLC25A1 | |
| SCHEMBL10657289 | 0.88 | ALDH1A1 (0.71) | CRHBPCRHR2ALDH1A1MAPTSLC25A1 | |
| SCHEMBL6151853 | 0.85 | CRHBP (0.62) | CRHBPCRHR2ALDH1A1MAPTSLC25A1 | |
| SCHEMBL8309888 | 0.80 | CRHBP (1.00) | CRHBPCRHR2ALDH1A1MAPTDNMT1 | |
| SCHEMBL9749511 | 0.80 | FFAR4 (0.71) | CRHBPCRHR2ALDH1A1MAPTSLC25A1 | |
| SCHEMBL1138740 | 0.80 | MAPT (0.69) | CRHBPCRHR2ALDH1A1MAPTSLC25A1 | |
| SCHEMBL28701969 | 0.80 | ALDH1A1 (0.64) | CRHBPCRHR2ALDH1A1MAPTSLC25A1 | |
| SCHEMBL29507647 | 0.80 | MAPT (0.69) | CRHBPCRHR2ALDH1A1MAPTSLC25A1 | |
| SCHEMBL5956066 | 0.80 | LMNA (0.57) | CRHBPCRHR2ALDH1A1MAPTSLC25A1 | |
| SCHEMBL10714707 | 0.79 | VCAM1 (0.45) | CRHBPCRHR2ALDH1A1MAPTSLC25A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4725283-A | NITROBENZENE DIRECT DYES FOR HUMAN HAIR | L'OREAL (FR) | 1988-02-16 | — | — | US | disclosed |
| US-4666453-A | Nitro-meta-phenylenediamines halogenated in the 6th position and their use in dyeing keratinic substances | L'OREAL (FR) | 1987-05-19 | — | — | US | disclosed |