SCHEMBL6152024

SCHEMBL6152024

Cc1ccc2[nH]c3c(c2c1)C(C)c1cccc(C)c1-3

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.40
NPC1 O15118 2/20 0.40
MEN1 O00255 2/20 0.40
POLB P06746 1/20 0.40
ALDH1A1 P00352 7/20 0.39
KDM4E B2RXH2 6/20 0.39
HPGD P15428 4/20 0.39
LMNA P02545 3/20 0.39
MAPT P10636 4/20 0.39
HSD17B10 Q99714 3/20 0.39
ALOX15 P16050 1/20 0.39
PTGS2 P35354 2/20 0.38
PTGES O14684 1/20 0.38
KIF11 P52732 3/20 0.37
ACHE P22303 1/20 0.37
MAPKAPK2 P49137 1/20 0.36
CYP1A2 P05177 1/20 0.36
CYP2A6 P11509 1/20 0.36
L3MBTL1 Q9Y468 3/20 0.36
GAA P10253 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6151877 0.72 KIF11 (0.47) KMT2ANPC1MEN1POLBALDH1A1
SCHEMBL27255942 0.72 KMT2A (0.45) KMT2ANPC1MEN1POLBALDH1A1
SCHEMBL29726988 0.67 KIF11 (0.67) KMT2ANPC1MEN1POLBALDH1A1
SCHEMBL13267003 0.67 KIF11 (0.67) KMT2ANPC1MEN1POLBALDH1A1
SCHEMBL30715262 0.64 KMT2A (0.54) KMT2ANPC1MEN1POLBALDH1A1
SCHEMBL21165684 0.64 KMT2A (0.54) KMT2ANPC1MEN1POLBALDH1A1
SCHEMBL7733259 0.63 MEN1 (0.44) KMT2AMEN1ALDH1A1KDM4EMAPT
SCHEMBL20247451 0.63 MEN1 (0.66) KMT2ANPC1MEN1POLBALDH1A1
SCHEMBL345690 0.63 KIF11 (0.67) KMT2ANPC1MEN1POLBALDH1A1
SCHEMBL29362354 0.63 KIF11 (0.67) KMT2ANPC1MEN1POLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1543045-A1 OLEFIN POLYMERIZATION PROCESS Equistar Chemicals, LP (US) 2005-06-22 EP disclosed
US-6765074-B2 SUPPORTED INDENOINDOLYL CATALYST SYSTEM AND AN ORGANOBORON OR ORGANOALUMINUM-TREATED SOLID EQUISTAR CHEMICALS, LP 2004-07-20 US disclosed
EP-1412399-A1 SUPPORTED OLEFIN POLYMERIZATION CATALYSTS Equistar Chemicals, LP (US) 2004-04-28 EP disclosed
WO-2004029102-A1 OLEFIN POLYMERIZATION PROCESS EQUISTAR CHEMICALS, LP (US) 2004-04-08 WO disclosed
US-20040063876-A1 Olefin polymerization process EQUISTAR CHEMICALS, LP 2004-04-01 US disclosed
US-6583242-B2 Alumoxane, organometallic complex containing an indenoindolyl ligand, an activator; copolymerizing ethylene with a C3-C10 alpha-olefin EQUISTAR CHEMICALS, LP 2003-06-24 US disclosed
US-20030050413-A1 Supported olefin polymerization catalysts EQUISTAR CHEMICALS, LP 2003-03-13 US disclosed
WO-2003011921-A1 SUPPORTED OLEFIN POLYMERIZATION CATALYSTS EQUISTAR CHEMICALS, LP (US) 2003-02-13 WO disclosed
US-6376629-B2 ORGANOMETALLIC COMPOUND EQUISTAR CHEMICALS, LP 2002-04-23 US disclosed
US-20010007848-A1 Single-site catalysts for olefin polymerization EQUISTAR CHEMICALS, L.P. 2001-07-12 US disclosed
US-6232260-B1 ORGANOMETALLIC COMPLEX COMPRISES A GROUP 3 TO 10 TRANSITION OR LANTHANIDE METAL, M, AND AT LEAST ONE INDENOINDOLYL LIGAND THAT IS .PI.-BONDED TO M. EQUISTAR CHEMICALS, L.P. 2001-05-15 US disclosed
WO-2001027125-A1 SINGLE-SITE CATALYSTS FOR OLEFIN POLYMERIZATION EQUISTAR CHEMICALS, L.P. (US) 2001-04-19 WO disclosed