SCHEMBL6152167

SCHEMBL6152167

C=C[n+]1cccc(N)c1-c1ccccc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 3/20 0.38
ALDH1A1 P00352 2/20 0.38
SLC22A2 O15244 1/20 0.33
SLC22A1 O15245 1/20 0.33
SLC22A3 O75751 1/20 0.33
SLC6A4 P31645 1/20 0.33
ALOX15 P16050 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
USP2 O75604 1/20 0.32
LMNA P02545 1/20 0.32
HSP90AA1 P07900 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
HPGD P15428 1/20 0.32
ALOX12 P18054 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32
MAOA P21397 1/20 0.32
CYP3A4 P08684 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4035931 0.67 KDM4E (0.32) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
SCHEMBL6152165 0.67 ALDH1A1 (0.43) HSD17B10ALDH1A1ALOX15KDM4EGAA
Hydrochloric Acid SCHEMBL4035925 0.65 KDM4E (0.32) ALDH1A1SLC22A2SLC22A1SLC22A3SLC6A4
SCHEMBL6151660 0.63 CYP3A4 (0.40) HSD17B10ALDH1A1ALOX15KDM4EMEN1
Dimethylamine SCHEMBL10340039 0.63 HDAC8 (0.33) SLC22A2SLC22A1SLC22A3SLC6A4KDM4E
Biphenyl SCHEMBL27516413 0.62 ALOX15 (0.71) HSD17B10ALDH1A1SLC22A2SLC22A1SLC22A3
SCHEMBL6656494 0.61 ACHE (0.44)
Biphenyl SCHEMBL27766939 0.60 ALDH1A1 (0.60) HSD17B10ALDH1A1SLC22A2SLC22A1SLC22A3
SCHEMBL1164410 0.59
SCHEMBL22003326 0.58 CYP3A4 (0.91) HSD17B10ALDH1A1ALOX15KDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1498106-A2 Composition containing a conductive polymer and at least one film-forming polymer, corresponding process and use L'OREAL (FR) 2005-01-19 EP claimed
EP-1498105-A2 Composition containing at least one conductive polymer and non-film forming rigid particles, corresponding process and use L'OREAL (FR) 2005-01-19 EP claimed